ReviewJournal of neuro-oncology2007
Atypical teratoid/rhabdoid tumor of the spine in an adult: case report and review of the literature.
Review in Journal of neuro-oncology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Atypical teratoid/rhabdoid tumor in adults: a systematic review of the literature with meta-analysis and additional reports of 4 cases.Journal of neuro-oncology · 2022Pooled it
- Radiological image features of the atypical teratoid/rhabdoid tumor in adults: a systematic review.Clinical neuroradiology · 2015Pooled it
- SMARCB1-related schwannomatosis and other SMARCB1-associated phenotypes: clinical spectrum and molecular pathogenesis.Familial cancer · 2025Review
- Epidemiology, Characteristics, and Prognostic Factors of Primary Atypical Teratoid/Rhabdoid Tumors in the Spinal Canal: A Systematic Review.Neurospine · 2024Article
- An adult with recurrent atypical teratoid rhabdoid tumor of the spine.CNS oncology · 2024Article
- Spinal atypical teratoid rhabdoid tumor-narrative review and report of a rare case managed with multimodality approach.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Characteristics of undiagnosed diseases network applicants: implications for referring providers.BMC health services research · 2018Article
- A Systematic Review of Atypical Teratoid Rhabdoid Tumor in Adults.Frontiers in oncology · 2018Article
- Primary atypical teratoid rhabdoid tumor in the adult spine.Surgical neurology international · 2017Article
- Atypical Teratoid Rhabdoid Tumor: Two Case Reports and an Analysis of Adult Cases with Implications for Pathophysiology and Treatment.Frontiers in neurology · 2017Article
- Cytologic diagnosis of atypical teratoid rhabdoid tumor based on touch imprint study: Report of a case with review of literature.Journal of education and health promotion · 2017Article
- Multifocal atypical teratoid/rhabdoid tumor: a rare entity.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Primary atypical teratoid/rhabdoid tumor of the spine in an adult patient.Surgical neurology international · 2016Article
- Atypical teratoid rhabdoid tumour of the spine: report of a case and literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2015Review
- Atypical teratoid/rhabdoid tumor in sellar turcica in an adult: A case report and review of the literature.Surgical neurology international · 2014Article
- Cutaneous malignant rhabdoid tumor in the palm of an adult.Rare tumors · 2013Article
- A complex karyotype in an atypical teratoid/rhabdoid tumor: case report and review of the literature.Journal of neuro-oncology · 2011Review
- Atypical teratoid/rhabdoid tumors in adults: a case report and treatment-focused review.Journal of clinical medicine research · 2011Article
- Atypical teratoid rhabdoid tumor (AT/RT) in adults: review of four cases.Journal of neuro-oncology · 2008Article
- A case of primary spinal atypical teratoid/rhabdoid tumor in a 5-year-old child.Journal of pediatric neurosciencesArticle
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
Abstract
Atypical teratoid/rhabdoid tumors (AT/RTs) are rare, malignant brain tumors which occur almost exclusively in infants and young children. There have been only 17 cases of AT/RT in adults reported in the medical literature and the rarity of this tumor makes the diagnosis in adults difficult. We describe a case of an AT/RT of the spinal cord in an adult. A 43-year old woman presented with neck and left upper extremity pain. An MRI demonstrated a mass lesion in the dorsal spinal cord extending from C4 to C6. The patient underwent a C3 through C7 laminectomy. In consultation with senior pathologists at other institutions, the lesion was initially diagnosed as a rhabdoid meningioma. Molecular genetic studies revealed monosomy 22 and loss of expression of the INI1 gene in 22q11.2. Subsequently, immunohistochemical studies revealed the absence of INI1 gene expression in the malignant cells, supporting the diagnosis of AT/RT. The patient underwent three additional surgical procedures for recurrent disease throughout the neuraxis secondary to leptomeningeal spread of the tumor. Despite aggressive surgical resection, adjuvant chemotherapy and radiation therapy, the patient succumbed to the disease two and a half years after her initial presentation. An unrestricted autopsy was performed. To our knowledge, this is the first case of a spinal atypical teratoid/rhabdoid tumor in an adult fully documented with molecular, immunohistochemical, cytogenetic and autopsy findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.