ArticleBioconjugate chemistry
Single cell fluorescence imaging using metal plasmon-coupled probe.
Article in Bioconjugate chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Synthesis of Fluorescent Core-Shell Metal Nanohybrids: A Versatile Approach.Materials (Basel, Switzerland) · 2016Article
- Light-Enhanced Fluorescence of Multi-Level Cavitands Possessing Pyridazine Upper rim.Journal of fluorescence · 2016Article
- Toxicological studies on silver nanoparticles: challenges and opportunities in assessment, monitoring and imaging.Nanomedicine (London, England) · 2011Review
- Fluorescent avidin-bound silver particle: a strategy for single target molecule detection on a cell membrane.Analytical chemistry · 2009Article
- Modification of single molecule fluorescence near metallic nanostructures.Laser & photonics reviews · 2009Article
- Metallic Nanostructures as Localized Plasmon Resonance Enhanced Scattering Probes for Multiplex Dark Field Targeted Imaging of Cancer Cells.The journal of physical chemistry. C, Nanomaterials and interfaces · 2009Article
- Enhanced fluorescence images for labeled cells on silver island films.Langmuir : the ACS journal of surfaces and colloids · 2008Article
- Single-cell fluorescence imaging using metal plasmon-coupled probe 2: single-molecule counting on lifetime image.Nano letters · 2008Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
This work constitutes the first fluorescent imaging of cells using metal plasmon-coupled probes (PCPs) at single cell resolution. N-(2-Mercapto-propionyl)glycine-coated silver nanoparticles were synthesized by reduction of silver nitrate using sodium borohyride and then succinimidylated via ligand exchange. Alexa Fluor 647-labeled concanavalin A (con A) was chemically bound to the silver particles to make the fluorescent metal plasmon-coupled probes. The fluorescence images were collected using a scanning confocal microscopy. The fluorescence intensity was observed to enhance 7-fold when binding the labeled con A on a single silver particle. PCPs were conjugated on HEK 293 A cells. Imaging results demonstrate that cells labeled by PCPs were 20-fold brighter than those by free labeled con A.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.