ArticlePhotosynthesis research
Reflections on the function of IsiA, a cyanobacterial stress-inducible, Chl-binding protein.
Article in Photosynthesis research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Photosystem I structural fusion with IsiA enhances light-harvesting capabilities of filamentous cyanobacterium during iron deficiency.Cell reports. Physical science · 2026Article
- A global transcriptional activator involved in the iron homeostasis in cyanobacteria.Science advances · 2024Article
- Structure-based Hamiltonian model for IsiA uncovers a highly robust pigment-protein complex.Journal of the Royal Society, Interface · 2020Article
- Transcriptome Analysis Reveals IsiA-Regulatory Mechanisms Underlying Iron Depletion and Oxidative-Stress Acclimation inApplied and environmental microbiology · 2020Article
- Function of the IsiA pigment-protein complex in vivo.Photosynthesis research · 2019Article
- Phycobilisome truncation causes widespread proteome changes in Synechocystis sp. PCC 6803.PloS one · 2017Article
- Transcriptional regulator PrqR plays a negative role in glucose metabolism and oxidative stress acclimation in Synechocystis sp. PCC 6803.Scientific reports · 2016Article
- Iron-Nutrient Interactions within Phytoplankton.Frontiers in plant science · 2016Review
- NADPH-Thioredoxin Reductase C Mediates the Response to Oxidative Stress and Thermotolerance in the Cyanobacterium Anabaena sp. PCC7120.Frontiers in microbiology · 2016Article
- Molecular investigation of the radiation resistance of edible cyanobacterium Arthrospira sp. PCC 8005.MicrobiologyOpen · 2015Article
- Functional role of PilA in iron acquisition in the cyanobacterium Synechocystis sp. PCC 6803.PloS one · 2014Article
- Whole genome comparison of six Crocosphaera watsonii strains with differing phenotypes.Journal of phycology · 2013Article
- Article
- Surplus photosynthetic antennae complexes underlie diagnostics of iron limitation in a cyanobacterium.PloS one · 2011Article
- Electrochromism: a useful probe to study algal photosynthesis.Photosynthesis research · 2010Review
- IsiA is required for the formation of photosystem I supercomplexes and for efficient state transition in synechocystis PCC 6803.PloS one · 2010Article
- A comprehensive analysis of the peroxiredoxin reduction system in the Cyanobacterium Synechocystis sp. strain PCC 6803 reveals that all five peroxiredoxins are thioredoxin dependent.Journal of bacteriology · 2009Article
- The mechanism of iron homeostasis in the unicellular cyanobacterium synechocystis sp. PCC 6803 and its relationship to oxidative stress.Plant physiology · 2009Article
- Article
- Small RNAs establish delays and temporal thresholds in gene expression.Biophysical journal · 2008Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The isiA gene encodes a protein that is similar to the Photosystem II chlorophyll-binding protein CP43, but lacks the entire large lumenal loop of over 100 amino acids. What is the function of this IsiA protein? Research on IsiA has traveled a long and interesting path since it was first discovered by its large accumulation during growth under iron-limited conditions. What appeared to be a simple on-off switch for isiA based on iron concentration has developed into a much richer and more intriguing set of possibilities that involve its expression and function. We provide an overview of isiA transcriptional regulation by many environmental factors and its proposed functions. We also describe the response to oxidative stress by cells that lack the IsiA protein. It is now clear that isiA expression can be de-repressed in the presence of normal iron levels and that the regulatory mechanisms can be linked to the inter-relationship between iron homeostasis and oxidative stress. The de facto transcriptional control of isiA expression has expanded to include regulation at both the transcriptional and post-transcriptional levels.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.