ArticleGenome biology2007
A haplome alignment and reference sequence of the highly polymorphic Ciona savignyi genome.
Article in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- MGA: a tool for haplotype-mixed assembly of long and accurate reads.Genome biology · 2026Article
- An Improved Chromosome-Level Genome Assembly and Comprehensive Annotation of the Model Ascidian Ciona savignyi.Scientific data · 2026Article
- Temporospatial hierarchy and allele-specific expression of zygotic genome activation revealed by distant interspecific urochordate hybrids.Nature communications · 2024Article
- Assembly of complete diploid-phased chromosomes from draft genome sequences.G3 (Bethesda, Md.) · 2022Article
- The Genome of the "Sea Vomit"Life (Basel, Switzerland) · 2021Article
- Ciliary photoreceptors in sea urchin larvae indicate pan-deuterostome cell type conservation.BMC biology · 2021Article
- Potential of genomic technologies to improve disease resistance in molluscan aquaculture.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Stem Cells and Innate Immunity in Aquatic Invertebrates: Bridging Two Seemingly Disparate Disciplines for New Discoveries in Biology.Frontiers in immunology · 2021Review
- Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava).Molecular ecology resources · 2020Article
- Sawfly Genomes Reveal Evolutionary Acquisitions That Fostered the Mega-Radiation of Parasitoid and Eusocial Hymenoptera.Genome biology and evolution · 2020Article
- A Nearly Complete Genome of Ciona intestinalis Type A (C. robusta) Reveals the Contribution of Inversion to Chromosomal Evolution in the Genus Ciona.Genome biology and evolution · 2019Article
- Haplotype-resolved genomes of geminivirus-resistant and geminivirus-susceptible African cassava cultivars.BMC biology · 2019Article
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- Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies.BMC bioinformatics · 2018Article
- De novo draft assembly of the Botrylloides leachii genome provides further insight into tunicate evolution.Scientific reports · 2018Article
- The State of "Frontiers in genetics · 2018Review
- Long-read sequence assembly of the firefly Pyrocoelia pectoralis genome.GigaScience · 2017Article
- Architectural delineation and molecular identification of extracellular matrix in ascidian embryos and larvae.Biology open · 2017Article
- The Whole-Genome and Transcriptome of the Manila Clam (Ruditapes philippinarum).Genome biology and evolution · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The sequence of Ciona savignyi was determined using a whole-genome shotgun strategy, but a high degree of polymorphism resulted in a fractured assembly wherein allelic sequences from the same genomic region assembled separately. We designed a multistep strategy to generate a nonredundant reference sequence from the original assembly by reconstructing and aligning the two 'haplomes' (haploid genomes). In the resultant 174 megabase reference sequence, each locus is represented once, misassemblies are corrected, and contiguity and continuity are dramatically improved.
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