ArticlePLoS biology2007
Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology.
Article in PLoS biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Recent Progress of Protein Tertiary Structure Prediction.Molecules (Basel, Switzerland) · 2024Review
- Toward the solution of the protein structure prediction problem.The Journal of biological chemistry · 2021Review
- The Saccharomyces cerevisiae Ncw2 protein works on the chitin/β-glucan organisation of the cell wall.Antonie van Leeuwenhoek · 2021Article
- Complete fold annotation of the human proteome using a novel structural feature space.Scientific reports · 2017Article
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- Structure prediction and analysis of DNA transposon and LINE retrotransposon proteins.The Journal of biological chemistry · 2013Article
- Highly abundant proteins favor more stable 3D structures in yeast.Biophysical journal · 2013Article
- The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis.Cell · 2013Article
- Ab Initio structure prediction for Escherichia coli: towards genome-wide protein structure modeling and fold assignment.Scientific reports · 2013Article
- A comparative assessment and analysis of 20 representative sequence alignment methods for protein structure prediction.Scientific reports · 2013Article
- A domain-centric solution to functional genomics via dcGO Predictor.BMC bioinformatics · 2013Article
- Evidence for the robustness of protein complexes to inter-species hybridization.PLoS genetics · 2012Article
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- Comparative microbial modules resource: generation and visualization of multi-species biclusters.PLoS computational biology · 2011Article
- The Proteome Folding Project: proteome-scale prediction of structure and function.Genome research · 2011Article
- BUD22 affects Ty1 retrotransposition and ribosome biogenesis in Saccharomyces cerevisiae.Genetics · 2010Article
- Boosting the prediction and understanding of DNA-binding domains from sequence.Nucleic acids research · 2010Article
- I-TASSER: a unified platform for automated protein structure and function prediction.Nature protocols · 2010Article
- Article
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Authors and funding
7 authors.
Funding
Abstract
Saccharomyces cerevisiae is one of the best-studied model organisms, yet the three-dimensional structure and molecular function of many yeast proteins remain unknown. Yeast proteins were parsed into 14,934 domains, and those lacking sequence similarity to proteins of known structure were folded using the Rosetta de novo structure prediction method on the World Community Grid. This structural data was integrated with process, component, and function annotations from the Saccharomyces Genome Database to assign yeast protein domains to SCOP superfamilies using a simple Bayesian approach. We have predicted the structure of 3,338 putative domains and assigned SCOP superfamily annotations to 581 of them. We have also assigned structural annotations to 7,094 predicted domains based on fold recognition and homology modeling methods. The domain predictions and structural information are available in an online database at http://rd.plos.org/10.1371_journal.pbio.0050076_01.
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