Evidence map›Paper›PMID 17373412›Full record

ReviewAlcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism2006

Treating smoking dependence in depressed alcoholics.

Nassima Ait-Daoud, Wendy J Lynch, J Kim Penberthy, Alison B Breland, Gabrielle R Marzani-Nissen, Bankole A Johnson

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nassima Ait-DaoudDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia, USA.
Wendy J Lynch
J Kim Penberthy
Alison B Breland
Gabrielle R Marzani-Nissen
Bankole A Johnson
University of Virginia · US

Funding

Pharmacologic Treatments in Emerging AdultsR01AA010522 · NIAAA · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOHNSON, BANKOLE A · 1995 to 2012
$7.0M
COMBINED PHARMACOTHERAPIES FOR ALCOHOLISMR01AA012964 · NIAAA · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOHNSON, BANKOLE A · 2001 to 2005
$3.4M
Medication Development for Cocaine DependenceR01DA017296 · NIDA · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOHNSON, BANKOLE A · 2005 to 2008
$2.4M
DO GENES &BRAIN ACTIVITY PREDICT ALCOHOL RISK?K23AA000329 · NIAAA · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI AIT-DAOUD, NASSIMA · 2001 to 2005
$830k
NIAAA NIH HHS AA10522-10NIAAA NIH HHS AA12964-01NIAAA NIH HHS K23 AA000329NIAAA NIH HHS K23 AA00329-01NIAAA NIH HHS R01 AA010522NIAAA NIH HHS R01 AA012964NIDA NIH HHS DA017296-01A1NIDA NIH HHS R01 DA017296
6 · The paper itself

Abstract

Alcoholism and nicotine dependence share many neurobiological underpinnings; the presence of one drug can cause a person to crave the other. Depressive illness can complicate comorbid alcohol and nicotine dependence by exacerbating the negative affect encountered during attempts to abstain from one or both drugs. Given the morbidity and mortality associated with cigarette smoking, it is imperative to identify treatments to promote smoking cessation and address comorbid psychiatric conditions contemporaneously. Pharmacotherapeutic options demonstrating varying degrees of efficacy and promise in preclinical and clinical studies include nicotine replacement therapy (NRT), selective serotonin reuptake inhibitors (SSRIs), bupropion, varenicline, tricyclic antidepressants, and bupropion plus NRT. Topiramate has shown potential for promoting smoking cessation in alcoholics, although its safety in depressed patients has not been fully explored. The efficacy of medications for treating nicotine dependence is generally enhanced by the inclusion of behavioral interventions such as cognitive behavioral therapy. When group cohesion and social support are stressed, success rates increase among depressed smokers undergoing smoking cessation treatment. Additional treatment strategies targeting dually dependent individuals with comorbid psychiatric disorders, including special populations such as women and adolescents, await further investigation.

Indexed as

Smoking CessationAlcoholismAntidepressive AgentsBupropionClinical Trials as TopicCognitive Behavioral TherapyCombined Modality TherapyComorbidityDepressive DisorderFructoseHumansNicotinePsychotherapy, GroupTopiramateAntidepressive AgentsBupropionFructoseNicotineTopiramate

Identifiers

PMID17373412
PMCPMC6527046
OpenAlexW2117502809

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.