ArticleEmerging infectious diseases2007
Primary pneumocystis infection in infants hospitalized with acute respiratory tract infection.
Article in Emerging infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Detection of Opportunistic Fungi from the Bronchoalveolar Lavage Specimens of Patients with Pulmonary Diseases.Advanced biomedical research · 2023Article
- Detection of Pneumocystis jirovecii and Toxoplasma gondii in patients with lung infections by a duplex qPCR assay.PLoS neglected tropical diseases · 2021Article
- An infant with X-linked anhidrotic ectodermal dysplasia with immunodeficiency presenting withClinical case reports · 2021Article
- Detection ofJournal of fungi (Basel, Switzerland) · 2021Article
- Diagnosis ofJournal of fungi (Basel, Switzerland) · 2020Article
- Pneumocystis primary infection in infancy: Additional French data and review of the literature.Medical mycology · 2020Article
- Review
- Acquired Immunodeficiency from Maternal Chemotherapy and Severe PrimaryCase reports in pediatrics · 2020Article
- Increase in secreted airway mucins and partial Muc5b STAT6/FoxA2 regulation during Pneumocystis primary infection.Scientific reports · 2019Article
- In vitro and in vivo activity of iclaprim, a diaminopyrimidine compound and potential therapeutic alternative against Pneumocystis pneumonia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Article
- High transient colonization by Pneumocystis jirovecii between mothers and newborn.European journal of pediatrics · 2017Article
- Importance of tissue sampling, laboratory methods, and patient characteristics for detection of Pneumocystis in autopsied lungs of non-immunosuppressed individuals.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Review
- Fungi that Infect Humans.Microbiology spectrum · 2017Review
- Colonisation with Pneumocystis jirovecii in Australian infants.Pathology · 2015Article
- Molecular detection ofCurrent medical mycology · 2015Article
- Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies.Cellular and molecular life sciences : CMLS · 2015Review
- Diagnosis of the primary infection by pneumocystis in autopsy specimens from two infants using lung impression smears (touch preps).Medical mycology case reports · 2014Article
- Diamidines versus Monoamidines as Anti-Pneumocystis Agents: An in Vivo Study.Pharmaceuticals (Basel, Switzerland) · 2013Article
- Near-universal prevalence of Pneumocystis and associated increase in mucus in the lungs of infants with sudden unexpected death.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Article
- Humoral immune responses to Pneumocystis jirovecii antigens in HIV-infected and uninfected young children with pneumocystis pneumonia.PloS one · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acquisition of Pneumocystis jirovecii infection early in life has been confirmed by serologic studies. However, no evidence of clinical illness correlated with the primary infection has been found in immunocompetent children. We analyzed 458 nasopharyngeal aspirates from 422 patients hospitalized with 431 episodes of acute respiratory tract infection (RTI) by using a real-time PCR assay. In 68 episodes in 67 infants, P. jirovecii was identified. The odds ratio (95% confidence interval) of a positive signal compared with the first quartile of age (7-49 days) was 47.4 (11.0-203), 8.7 (1.9-39.7), and 0.6 (0.1-6.7) for infants in the second (50-112 days), third (113-265 days), and fourth (268-4,430 days) age quartiles, respectively. Infants with an episode of upper RTI (URTI) were 2.0 (1.05-3.82) times more likely to harbor P. jirovecii than infants with a lower RTI. P. jirovecii may manifest itself as a self-limiting URTI in infants, predominantly those 1.5-4 months of age.
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