ArticleBiophysical journal2007
Multiplex SNP discrimination.
Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Low-Cost Platform for Multiplexed Electrochemical Melting Curve Analysis.ACS measurement science au · 2022Article
- Salt concentration effects on equilibrium melting curves from DNA microarrays.Biophysical journal · 2010Article
- Label-free microarray imaging for direct detection of DNA hybridization and single-nucleotide mismatches.Biosensors & bioelectronics · 2010Article
- Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Real-time DNA microarrays: reality check.Biochemical Society transactions · 2009Review
- Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays.BMC genomics · 2008Article
- Kinetics of multiplex hybridization: mechanisms and implications.Biophysical journal · 2008Article
- DNA multiplex hybridization on microarrays and thermodynamic stability in solution: a direct comparison.Nucleic acids research · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Multiplex hybridization reactions of perfectly matched duplexes and duplexes containing a single basepair mismatch (SNPs) were investigated on DNA microarrays. Effects of duplex length, G-C percentage, and relative position of the SNP on duplex hybridization and SNP resolution were determined. Our theoretical model of multiplex hybridization accurately predicts observed results and implicates target concentration as a critical variable in multiplex SNP detection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.