ArticleBiophysical journal2007
Stepwise movements in vesicle transport of HER2 by motor proteins in living cells.
Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 78 citations in OpenAlex.
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- Strategies for Non-Covalent Attachment of Antibodies to PEGylated Nanoparticles for Targeted Drug Delivery.International journal of nanomedicine · 2024Review
- Resolving Single-Nanoconstruct Dynamics during Targeting and Nontargeting Live-Cell Membrane Interactions.ACS nano · 2019Article
- 3D rotational motion of an endocytic vesicle on a complex microtubule network in a living cell.Biomedical optics express · 2019Article
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- Predictive diagnosis of the risk of breast cancer recurrence after surgery by single-particle quantum dot imaging.Scientific reports · 2015Article
- A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.The Journal of biological chemistry · 2014Article
- Nano-scale measurement of biomolecules by optical microscopy and semiconductor nanoparticles.Frontiers in physiology · 2014Review
- Near-infrared quantum dots for HER2 localization and imaging of cancer cells.International journal of nanomedicine · 2014Article
- Four-dimensional spatial nanometry of single particles in living cells using polarized quantum rods.Biophysical journal · 2013Article
- Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis.Molecular and cellular biology · 2013Article
- A non-invasive imaging for the in vivo tracking of high-speed vesicle transport in mouse neutrophils.Scientific reports · 2013Article
- Acroframosome-dependent KIFC1 facilitates acrosome formation during spermatogenesis in the caridean shrimp Exopalaemon modestus.PloS one · 2013Article
- KIF1Bβ transports dendritically localized mRNPs in neurons and is recruited to synapses in an activity-dependent manner.Cellular and molecular life sciences : CMLS · 2013Article
- Quantum dots: synthesis, bioapplications, and toxicity.Nanoscale research letters · 2012Article
- Effects of paclitaxel on EGFR endocytic trafficking revealed using quantum dot tracking in single cells.PloS one · 2012Article
- Exploring transduction mechanisms of protein transduction domains (PTDs) in living cells utilizing single-quantum dot tracking (SQT) technology.Sensors (Basel, Switzerland) · 2012Review
- Force-velocity relationship for multiple kinesin motors pulling a magnetic bead.European biophysics journal : EBJ · 2011Article
- Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Single particle tracking confirms that multivalent Tat protein transduction domain-induced heparan sulfate proteoglycan cross-linkage activates Rac1 for internalization.The Journal of biological chemistry · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The stepwise movements generated by myosin, dynein, and kinesin were observed in living cells in an attempt to understand the molecular mechanisms of movement within cells. First, the sequential process of the transport of vesicles, including human epidermal factor 2 receptor, after endocytosis was observed for long periods in three dimensions using quantum dots (QDs) and a three-dimensional confocal microscope. QD vesicles, after being endocytosed into the cells, moved along the membrane by transferring actin filaments and were then rapidly transported toward the nucleus along microtubules. Second, the position of vesicles was detected with a precision up to 1.9 nm and 330 micros using a new two-dimensional tracking method. The movement of the QDs transported by myosin VI lying just beneath the cell membrane consisted of 29- and 15-nm steps with a transition phase between these two steps. QD vesicles were then transported toward the nucleus or away from the nucleus toward the cell membrane with successive 8-nm steps. The stepwise movements of these motor proteins in cells were observed using new imaging methods that allowed the molecular mechanisms underlying traffic to and from the membrane to be determined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.