Evidence map›Paper›PMID 17366606›Full record

ArticleThe Journal of comparative neurology2007

Nonintegrin laminin receptor precursor protein is expressed on olfactory stem and progenitor cells.

Woochan Jang, Kwang Pyo Kim, James E Schwob

Abstract read
In one paragraph

Article in The Journal of comparative neurology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Globose basal cells for spinal cord regeneration.Neural regeneration research · 2017
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Expression of pax6 and sox2 in adult olfactory epithelium.The Journal of comparative neurology · 2010
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Woochan JangDepartment of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Kwang Pyo Kim
James E Schwob

Funding

REGULATION OF NEUROGENESIS IN OLFACTORY EPITHELIUMR01DC002167 · NIDCD · UPSTATE MEDICAL UNIVERSITY · PI SCHWOB, JAMES E. · 1994 to 2016
$5.2M
Strategies for Restoring Olfactory NeurogenesisR21DC006517 · NIDCD · TUFTS UNIVERSITY BOSTON · PI SCHWOB, JAMES E · 2003 to 2004
$317k
NIDCD NIH HHS R01 DC002167NIDCD NIH HHS R21 DC006517
6 · The paper itself

Abstract

The biochemical identification and immunocytochemical characterization of a cell surface antigen, expressed on globose basal cells (GBCs) of the rodent olfactory epithelium (OE), are described. The monoclonal antibody (MAb) GBC-3 recognizes a surface protein, confirmed by both live cell staining and fluorescence-activated cell sorting. Two-dimensional SDS-PAGE/Western blot followed by tandem mass spectrometry demonstrates that the cell surface GBC-3 antigen is the 40 kDa laminin receptor precursor protein. The MAb GBC-3 labels the vast majority of cells among the GBC population and does not stain either sustentacular cells or horizontal basal cells (HBCs) in the normal rat OE. After epithelial lesion by exposure to methyl bromide, the remaining cells, which are mostly GBCs, are heavily stained by GBC-3, and colabeled with GBC-3 and sustentacular cell or HBC markers. GBC-3 will be a potentially useful tool for identifying and characterizing GBCs.

Indexed as

Receptors, LamininAnimalsCells, CulturedDiagnostic ImagingEmbryo, MammalianEpitheliumFlow CytometryGene Expression Regulation, DevelopmentalMass SpectrometryNerve Tissue ProteinsOlfactory BulbProtein PrecursorsRatsRats, Sprague-DawleyStem CellsNerve Tissue ProteinsProtein PrecursorsReceptors, Laminin

Identifiers

PMID17366606
PMCPMC3882313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.