ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2007
Look who's talking: communication and quorum sensing in the bacterial world.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 282 papers.
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Who cites it
282 citing papers in PubMed.
- Review
- Identification ofMicroorganisms · 2026Article
- Discovery of triazole-tethered glycinate and propanoate derivatives bearing a thiolactone moiety as quorum sensing inhibitors ofRSC advances · 2026Article
- Molecular Mechanisms of Algicidal Bacteria in Controlling Harmful Algal Blooms: Advances in Bacteria-Algae Interactions.Environmental microbiology reports · 2026Review
- Marine BacteriumJournal of natural products · 2026Article
- Article
- Targeting calcineurin: a synergistic strategy with caspofungin to induce farnesol-mediated quorum sensing in Nakaseomyces glabrata-an inoculum-dependent tale.The Biochemical journal · 2025Article
- The Quorum Sensing-Controlled Competence Regulon Drives HACS infectious diseases · 2025Article
- Do farnesol and tyrosol production inVirulence · 2025Article
- An agent-based model of metabolic signaling oscillations in Bacillus subtilis biofilms.PLoS computational biology · 2025Article
- Dynamics of bacterial biofilm development imaged using light sheet fluorescence microscopy.Biochemistry and biophysics reports · 2025Article
- Quorum sensing modulates microbial community structure through regulation of secondary metabolites.mSphere · 2025Article
- Deciphering the Regulatory Role and Molecular Interactions That Drive the Competence Regulon Quorum Sensing Circuitry inBiochemistry · 2025Article
- Exploring the microbial communities in coastal cenote and their hidden biotechnological potential.Microbial genomics · 2025Article
- A Novel Screening System to Characterize and Engineer Quorum Quenching Lactonases.Biotechnology and bioengineering · 2025Article
- Effects of bcsE, luxS and rfaG genes on the physiology and pathogenicity of Salmonella Typhimurium.Archives of microbiology · 2025Article
- Light-Based Juxtacrine Signaling Between Synthetic Cells.Small science · 2025Article
- Article
- Cinnamoyl lipids as novel signaling molecules modulate the physiological metabolism of cross-phylum microorganisms.Communications biology · 2024Article
- Manipulating the physical distance between cells during soil colonization reveals the importance of biotic interactions in microbial community assembly.Environmental microbiome · 2024Article
222 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
For many years bacteria were considered primarily as autonomous unicellular organisms with little capacity for collective behaviour. However, we now appreciate that bacterial cells are in fact, highly communicative. The generic term 'quorum sensing' has been adopted to describe the bacterial cell-to-cell communication mechanisms which co-ordinate gene expression usually, but not always, when the population has reached a high cell density. Quorum sensing depends on the synthesis of small molecules (often referred to as pheromones or autoinducers) that diffuse in and out of bacterial cells. As the bacterial population density increases, so does the synthesis of quorum sensing signal molecules, and consequently, their concentration in the external environment rises. Once a critical threshold concentration has been reached, a target sensor kinase or response regulator is activated (or repressed) so facilitating the expression of quorum sensing-dependent genes. Quorum sensing enables a bacterial population to mount a co-operative response that improves access to nutrients or specific environmental niches, promotes collective defence against other competitor prokaryotes or eukaryotic defence mechanisms and facilitates survival through differentiation into morphological forms better able to combat environmental threats. Quorum sensing also crosses the prokaryotic-eukaryotic boundary since quorum sensing-dependent signalling can be exploited or inactivated by both plants and mammals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.