Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2007
House dust mite allergen avoidance and self-management in allergic patients with asthma: randomised controlled trial.
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- House dust mite control measures for asthma.The Cochrane database of systematic reviews · 2008Pooled it
- House dust mite allergen avoidance strategies for the treatment of allergic asthma: A hypothesis-generating meta-analysis.The World Allergy Organization journal · 2024Review
- Environmental allergen reduction in asthma management: an overview.Frontiers in allergy · 2023Review
- 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group.The Journal of allergy and clinical immunology · 2020Review
- The Indoor Environment and Childhood Asthma.Current allergy and asthma reports · 2020Review
- A meta-analysis of baseline characteristics in trials on mite allergen avoidance in asthmatics: room for improvement.Clinical and translational allergy · 2020Review
- A reintroduction of environmental mite allergen control strategies for asthma treatment and the debate on their effectiveness.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Review
- The Importance of Allergen Avoidance in High Risk Infants and Sensitized Patients: A Meta-analysis Study.Allergy, asthma & immunology research · 2014Article
- Environmental remediation in the treatment of allergy and asthma: latest updates.Current allergy and asthma reports · 2014Review
- Impact of environmental controls on childhood asthma.Current allergy and asthma reports · 2011Review
- The impact of a program for control of asthma in a low-income setting.The World Allergy Organization journal · 2010Article
- Current challenges in asthma.The British journal of general practice : the journal of the Royal College of General Practitioners · 2007Article
- Home Environmental Interventions for House Dust Mite.The journal of allergy and clinical immunology. In practiceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe efficacy of bed covers that are impermeable to house dust mites has been disputed.
aimThe aim of the present study was to investigate whether the combination of 'house dust mite impermeable' covers and a self-management plan, based on peak flow values and symptoms, leads to reduced use of inhaled corticosteroids (ICS) than self-management alone. DESIGN OF STUDY: Prospective, randomised, double blind, placebo-controlled trial.
settingPrimary care in a south-eastern region of the Netherlands.
methodAsthma patients aged between 16 and 60 years with a house dust mite allergy requiring ICS were randomised to intervention and placebo groups. They were trained to use a self-management plan based on peak flow and symptoms. After a 3-month training period, the intervention commenced using house dust mite impermeable and placebo bed covers. The follow-up period was 2 years. Primary outcome was the use of ICS; secondary outcomes were peak expiratory flow parameters, asthma control, and symptoms.
resultsOne hundred and twenty-six patients started the intervention with house dust mite impermeable or placebo bed covers. After 1 and 2 years, significant differences in allergen exposure were found between the intervention and control groups (P<0.001). No significant difference between the intervention and control groups was found in the dose of ICS (P = 0.08), morning peak flow (P = 0.52), peak flow variability (P = 0.36), dyspnoea (P = 0.46), wheezing (P = 0.77), or coughing (P = 0.41). There was no difference in asthma control between the intervention and control groups.
conclusionHouse dust mite impermeable bed covers combined with self-management do not lead to reduced use of ICS compared with self-management alone.
Indexed as
Identifiers
17359604PMC2042544What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.