ArticleImmunogenetics2007
Species-specific evolution of the FcR family in endothermic vertebrates.
Article in Immunogenetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Characterization of a membrane Fcγ receptor in largemouth bass (Micropterus saloumoides) and its response to bacterial challenge.Fish physiology and biochemistry · 2024Article
- No evidence for a direct extracellular interaction between human Fc receptor-like 3 (MAIA) and the sperm ligand IZUMO1.Science advances · 2024Article
- FCRL1 immunoregulation in B cell development and malignancy.Frontiers in immunology · 2023Review
- MAIA, Fc receptor-like 3, supersedes JUNO as IZUMO1 receptor during human fertilization.Science advances · 2022Article
- Immunoglobulin-like receptors and the generation of innate immune memory.Immunogenetics · 2022Review
- Review
- Polymorphisms in Fc Gamma Receptors and Susceptibility to Malaria in an Endemic Population.Frontiers in immunology · 2020Review
- Evolution of Fc Receptor-Like Scavenger in Mammals.Frontiers in immunology · 2020Article
- Unraveling the LRC Evolution in Mammals: IGSF1 and A1BG Provide the Keys.Genome biology and evolution · 2019Article
- FCRL regulation in innate-like B cells.Annals of the New York Academy of Sciences · 2015Review
- Article
- Expansion and diversification of the signaling capabilities of the CD2/SLAM family in Xenopodinae amphibians.Immunogenetics · 2011Article
- Article
- Cutting edge: FcR-like 6 is an MHC class II receptor.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites.Developmental and comparative immunology · 2010Article
- A monomeric chicken IgY receptor binds IgY with 2:1 stoichiometry.The Journal of biological chemistry · 2009Article
- Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
- Origin and evolution of the vertebrate leukocyte receptors: the lesson from tunicates.Immunogenetics · 2009Article
- The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution.BMC evolutionary biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In primates and rodents, the extended FcR family is comprised of three subsets: classical FcRs, structurally diverse cell surface receptors currently designated FCRL1-FCRL6, and intracellular proteins FCRLA and FCRLB. Using bioinformatic analysis, we revealed the FcR-like genes of the same three subsets in the genome of dog, another representative of placental mammals, and in the genome of short-tailed opossum, a representative of marsupials. In contrast, a single FcR-like gene was found in the current version of the chicken genome. This in silico finding was confirmed by the gene cloning and subsequent Southern blot hybridization. The chicken FCRL gene encodes a cell surface receptor with the extracellular region composed of four Ig-like domains of the D1-, D2-, D3-, and D4-subtypes. The gene is expressed in lymphoid and non-lymphoid tissues. Phylogenetic analysis of the mammalian and chicken genes suggested that classical FcRs, FCRLA, and FCRLB emerged after the mammalian-avian split but before the eutherian-marsupial radiation. The data obtained show that the repertoire of the classical FcRs and surface FcR-like proteins in mammalian species was shaped by an extensive recombination process, which resulted in domain shuffling and species-specific gain and loss of distinct exons or entire genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.