ArticleNeurocritical care2007
H2O coma.
Article in Neurocritical care, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake.Nature communications · 2020Article
- SLC9A4 in the organum vasculosum of the lamina terminalis is a [NaPflugers Archiv : European journal of physiology · 2020Article
- Short-term Effects of Hypertonic Shock on NaZoological studies · 2016Article
- Sodium sensing in the brain.Pflugers Archiv : European journal of physiology · 2015Review
- Physiological variation of segmented OCT retinal layer thicknesses is short-lasting.Journal of neurology · 2013Article
- Article
- Marathon related death due to brainstem herniation in rehydration-related hyponatraemia: a case report.Journal of medical case reports · 2007Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWater intoxication is a rare cause of coma. The leading causes of excessive hydration are endurance exercise, drug abuse, iatrogenic, cerebral salt wasting, or psychiatric conditions. Self-induced water intoxication in an otherwise healthy person is exceedingly rare.
methodsSingle patient case report and review of the literature.
resultsWe describe a previously fit and healthy 13-year-old girl who was admitted to the Accident and Emergency department in a comatose state following an unwitnessed seizure. On examination she had a fluctuating Glasgow Coma Score, bilateral mydriatic pupils that responded poorly to light, and an upgoing right plantar. Blood pressure, pulse rate, and oximetry, as well as body mass index, were normal. Routine blood examination revealed hyponatremia, hypochloremia, and a low hematocrit. Water intoxication was suspected and confirmed by reduced urine sodium, serum, and urine osmolality. The computed tomographic brain scan, lumbar puncture opening pressure, and cerebrospinal fluid examination were all normal. She regained consciousness and was fully orientated within 24 hours following intravenous NaCl administration. In this case, thirst without any other apparent pathology led to voluntary water intoxication.
conclusionsOur case illustrates the classic picture of self-induced water intoxication in a previously fit and healthy patient.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.