Evidence map›Paper›PMID 17354817›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2006

Tumor therapeutic response and vessel tortuosity: preliminary report in metastatic breast cancer.

Elizabeth Bullitt, Nancy U Lin, Matthew G Ewend, Donglin Zeng, Eric P Winer, Lisa A Carey, J Keith Smith

Open access · bronzeAbstract readControlled Clinical Trial
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Characterization of an Array-Based Dual-Frequency Transducer for Superharmonic Contrast Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  3. Review
  4. Article
  5. [Diagnostic test for detection of cervical lymph node metastasis from oral squamous cell carcinoma via infrared thermal imaging].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2019
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elizabeth BullittCASILab, CB # 7062, University of North Carolina, Chapel Hill, NC 27599, USA. bullitt@med.unc.edu
Nancy U Lin
Matthew G Ewend
Donglin Zeng
Eric P Winer
Lisa A Carey
J Keith Smith
University of North Carolina at Chapel Hill · USDana-Farber/Harvard Cancer Center · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KATHERINE A. HOADLEY · 1992 to 2026
$59.3M
Zonisamide in Patients with Neuropathic Pain Associated with Diabetic NeuropathyM01RR000046 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOY, MELANIE S · 1985 to 2008
$38.5M
Physician Scientist Training in Cancer ResearchT32CA009172 · NCI · DANA-FARBER CANCER INSTITUTE · PI Jennifer R Brown, James A. DeCaprio · 1985 to 2026
$17.1M
SPORE IN BREAST CANCERP50CA058185 · NCI · GEORGETOWN UNIVERSITY · PI DICKSON, ROBERT B. · 1992 to 2004
$4.0M
3D Cerebral Vessel Location for Surgical PlanningR01EB000219 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULLITT, ELIZABETH · 2002 to 2008
$3.0M
SPECIALIZED PROGRAM OF RESEARCH EXCELLENCE/BREAST CANCERP20CA058186 · NCI · UNIVERSITY OF TEXAS MD ANDERSON CAN CTR · PI HORTOBAGYI, GABRIEL N · 1992 to 1994
–
NCI NIH HHS P30 CA016086NCI NIH HHS P30CA16086-29S1NCI NIH HHS P30CA58223NCI NIH HHS P50 CA058185NCI NIH HHS P50 CA058223NCI NIH HHS P50CA58186-AV-55P2NCI NIH HHS T32 CA009172NCRR NIH HHS M01 RR000046NCRR NIH HHS M01RR00046NIBIB NIH HHS R01 EB000219NIBIB NIH HHS R01EB000219
6 · The paper itself

Abstract

No current non-invasive method is capable of assessing the efficacy of brain tumor therapy early during treatment. We outline an approach that evaluates tumor activity via statistical analysis of vessel shape using vessels segmented from MRA. This report is the first to describe the changes in vessel shape that occur during treatment of metastatic brain tumors as assessed by sequential MRA. In this preliminary study of 16 patients undergoing treatment for metastatic breast cancer we conclude that vessel shape may predict tumor response several months in advance of traditional methods.

Indexed as

AdolescentAdultAgedBrain NeoplasmsBreast NeoplasmsContrast MediaFemaleGadoliniumHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNeovascularization, PathologicPilot ProjectsPrognosisContrast MediaGadolinium

Identifiers

PMID17354817
PMCPMC2504703
OpenAlexW1590477294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.