ArticleScandinavian journal of primary health care2007
Can selective serotonin inhibitor drugs in elderly patients in nursing homes be reduced?
Article in Scandinavian journal of primary health care, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Health care professionals' attitudes towards deprescribing in older patients with limited life expectancy: A systematic review.British journal of clinical pharmacology · 2019Pooled it
- The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta-analysis.British journal of clinical pharmacology · 2016Pooled it
- Medication withdrawal trials in people aged 65 years and older: a systematic review.Drugs & aging · 2008Pooled it
- Barricades and brickwalls--a qualitative study exploring perceptions of medication use and deprescribing in long-term care.BMC geriatrics · 2016Article
- Treatment decisions on antidepressants in nursing homes: a qualitative study.Scandinavian journal of primary health care · 2011Article
- Measuring body mass index (BMI) in nursing home residents: the usefulness of measurement of arm span.Scandinavian journal of primary health care · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether treatment with selective serotonin reuptake inhibitors (SSRIs) could be withdrawn for elderly residents who had been on treatment for at least one year and to evaluate a method for systematic drug review.
designOpen, prospective, interventional study.
settingFour counties in Sweden. SUBJECTS: Elderly residents at 19 nursing homes, with ongoing treatment with SSRIs for more than one year.
main outcome measuresClinical evaluation, registration of drugs used and rating with Montgomery-Asberg Depression Rating Scale (MADRS). A semi-structured telephone interview with 15 participating physicians and 19 nurses.
resultsAbout one-third of all 822 residents in the nursing homes had ongoing antidepressant treatment, predominantly with SSRIs; 75% of them had been treated with SSRIs for at least one year and 119 (60%) of these were considered eligible for the study. The intervention was judged successful in 52% of these residents of whom 88% had a MADRS rating of less than 20 points. The GPs and the nurses experienced the method as practicable.
conclusionsWithdrawal of SSRI treatment was successful in the majority of cases. The MADRS may be a valuable addition to clinical evaluation when deciding whether to end or continue SSRI treatment.
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Registered trials
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