ArticleEpidemiology and infection2008
Ten years of viral and non-bacterial serology in adults with cystic fibrosis.
Article in Epidemiology and infection, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Prevalence and Clinical Impact of Respiratory Viral Infections from the STOP2 Study of Cystic Fibrosis Pulmonary Exacerbations.Annals of the American Thoracic Society · 2024Trial
- Coverage and predictors of influenza vaccination in patients with cystic fibrosis in a campaign with a mobile phone text messaging intervention.Human vaccines & immunotherapeutics · 2019Article
- Multiplex PCR reveals that viruses are more frequent than bacteria in children with cystic fibrosis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017Article
- Cooperative pathogenicity in cystic fibrosis: Stenotrophomonas maltophilia modulates Pseudomonas aeruginosa virulence in mixed biofilm.Frontiers in microbiology · 2015Article
- Differential responses to rhinovirus- and influenza-associated pulmonary exacerbations in patients with cystic fibrosis.Annals of the American Thoracic Society · 2014Article
- Oral, inhaled, and intravenous antibiotic choice for treating pulmonary exacerbations in cystic fibrosis.Pediatric pulmonology · 2013Article
- Spectrum of viral infections in patients with cystic fibrosis.European journal of microbiology & immunology · 2012Review
- Shortness of breath in a CF patient: not always the chest.BMJ case reports · 2011Article
- Pseudomonas aeruginosa suppresses interferon response to rhinovirus infection in cystic fibrosis but not in normal bronchial epithelial cells.Infection and immunity · 2011Article
- Respiratory Syncytial Virus Prophylaxis in Special Populations: Is it Something Worth Considering in Cystic Fibrosis and Immunosuppression?The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2011Article
- Pulmonary exacerbations in cystic fibrosis with negative bacterial cultures.Pediatric pulmonology · 2010Article
- Palivizumab, pneumococcal and influenza vaccination in cystic fibrosis.Journal of the Royal Society of Medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viral infections are associated with pulmonary exacerbations in children with cystic fibrosis (CF), but few studies have addressed the frequency in adults. This paper investigates the frequency and impact of viral infections in adults with CF receiving intravenous antibiotics. Pre- and post-treatment spirometry, inflammatory markers and antibody titres against influenza A, influenza B, adenovirus, respiratory syncytial virus, Mycoplasma pneumoniae, Chlamydia psittaci, and Coxiella burnetti were analysed over a 10-year period. Non-bacterial infections were identified in 5.1% of 3156 courses of treatment. The annual incidence of admissions per patient associated with viral infection was 4.9%. The presence of viral infection in association with a pulmonary exacerbation did not adversely affect lung function or inflammatory markers in the short term. Adults with CF have a lower incidence of respiratory viral infections associated with pulmonary exacerbations requiring intravenous antibiotics compared to children and infants with CF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.