ArticleJournal of general internal medicine2007
Gender differences in aspirin use among adults with coronary heart disease in the United States.
Article in Journal of general internal medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Secondary prevention of atherosclerotic cardiovascular disease in older adults: a scientific statement from the American Heart Association.Circulation · 2013Guideline
- Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease.JAMA network open · 2026Article
- Article
- National Trends in Aspirin Use and Expenditures in the United States: Analysis of The Medical Expenditure Panel Survey 2000-2021.Cardiology and therapy · 2024Article
- Aspirin for cardiovascular disease prevention among adults in the United States: Trends, prevalence, and participant characteristics associated with use.American journal of preventive cardiology · 2021Article
- Prescription Rates for Antiplatelet Therapy (APT) in Coronary Artery Disease (CAD) - What Benchmark are We Aiming at in Continuing Medical Education (CME)?Journal of European CME · 2020Article
- Aspirin Use among Adults with Cardiovascular Disease in the United States: Implications for an Intervention Approach.Journal of clinical medicine · 2019Article
- Different time trends by gender for the incidence of Hodgkin's lymphoma among young adults in the USA: a birth cohort phenomenon.Cancer causes & control : CCC · 2014Article
- Sex, socioeconomic status, access to cardiac catheterization, and outcomes for acute coronary syndromes in the context of universal healthcare coverage.Circulation. Cardiovascular quality and outcomes · 2014Article
- How does gender influence the recognition of cardiovascular risk and adherence to self-care recommendations?: A study in Polish primary care.BMC family practice · 2013Article
- The quality of primary care in a country with universal health care coverage.Journal of general internal medicine · 2011Article
- Neighborhood socioeconomic status, Medicaid coverage and medical management of myocardial infarction: atherosclerosis risk in communities (ARIC) community surveillance.BMC public health · 2010Article
- Use of antithrombotic agents among U.S. stroke survivors, 2000-2006.American journal of preventive medicine · 2010Article
- Impact of aspirin on pancreatic cancer in the elderly: analysis of socioeconomic status and outcomes of national matched cohorts.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundAspirin reduces mortality for men and women with coronary heart disease (CHD). Previous research suggests women with acute coronary syndromes receive less aggressive care, including less frequent early administration of aspirin. The presence of gender differences in aspirin use for secondary prevention is less clear.
objectiveTo determine if a gender difference exists in the use of aspirin for secondary prevention among individuals with CHD.
designWe analyzed data from the nationally representative 2000-2002 Medical Expenditure Panel Surveys to determine the prevalence of regular aspirin use among men and women with CHD.
participantsParticipants, 1,869, 40 years and older who reported CHD or prior myocardial infarction.
resultsWomen were less likely than men to use aspirin regularly (62.4% vs 75.6%, p < .001) even after adjusting for demographic, socioeconomic and clinical characteristics (adjusted OR = 0.62, 95% CI, 0.48-0.79). This difference narrowed but remained significant when the analysis was limited to those without self-reported contraindications to aspirin (79.8% vs 86.4%, P = .002, adjusted OR = 0.68, 95% CI, 0.48-0.97). Women were more likely than men to report contraindications (20.5% vs 12.5%, P < .001). Differences in aspirin use were greater between women and men with private health insurance (61.8% vs 79.0%, P < .001, adjusted OR = 0.48, 95% CI, 0.35-0.67) than among those with public coverage (62.5% vs 70.7%, P = .04, adjusted OR = 0.74, 95% CI, 0.50-1.11) (P < .001 for gender-insurance interaction).
conclusionWe found a gender difference in aspirin use among patients with CHD not fully explained by differences in patient characteristics or reported contraindications. These findings suggest a need for improved secondary prevention of cardiovascular events for women with CHD.
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