ArticleLearning & memory (Cold Spring Harbor, N.Y.)2007
Hormonal and monoamine signaling during reinforcement of hippocampal long-term potentiation and memory retrieval.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- The Modulation by the Locus Coeruleus of Recent and Remote Memory Retrieval is Activity-Dependent.Hippocampus · 2025Article
- The role of hippocampus in memory reactivation: an implication for a therapeutic target against opioid use disorder.Current addiction reports · 2022Review
- Atomoxetine improves hippocampal cell proliferation but not memory in Doxorubicin-treated adult male rats.Veterinary medicine and science · 2020Article
- Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task.Frontiers in aging neuroscience · 2019Article
- R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity.PloS one · 2017Article
- Individual Differences in Male Rats in a Behavioral Test Battery: A Multivariate Statistical Approach.Frontiers in behavioral neuroscience · 2017Article
- Concerted Gene Expression of Hippocampal Steroid Receptors during Spatial Learning in Male Wistar Rats: A Correlation Analysis.Frontiers in behavioral neuroscience · 2016Article
- Behavioural and Electrophysiological Evidence of Impaired Learning and Memory in Male Sprague Dawley Rats following Subchronic Exposure to Standardised Methanolic Extract of Mitragyna speciosa Korth.The Malaysian journal of medical sciences : MJMS · 2015Article
- Neuromodulatory signaling in hippocampus-dependent memory retrieval.Hippocampus · 2015Review
- Mapping and deciphering neural codes of NMDA receptor-dependent fear memory engrams in the hippocampus.PloS one · 2013Article
- Estrogen receptor α functions in the regulation of motivation and spatial cognition in young male rats.PloS one · 2013Article
- Differential consolidation and pattern reverberations within episodic cell assemblies in the mouse hippocampus.PloS one · 2011Article
- Balanced dopamine is critical for pattern completion during associative memory recall.PloS one · 2010Article
- Article
- Hippocampal testosterone relates to reference memory performance and synaptic plasticity in male rats.Frontiers in behavioral neuroscience · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently it was shown that holeboard training can reinforce, i.e., transform early-LTP into late-LTP in the dentate gyrus during the initial formation of a long-term spatial reference memory in rats. The consolidation of LTP as well as of the reference memory was dependent on protein synthesis. We have now investigated the transmitter systems involved in this reinforcement and found that LTP-consolidation and memory retrieval were dependent on beta-adrenergic, dopaminergic, and mineralocorticoid receptor (MR) activation, whereas glucocorticoid receptors (GRs) were not involved. Blockade of the beta-adrenergic signaling pathway significantly increased the number of reference memory errors compared with MR and dopamine receptor inhibition. In addition, beta-adrenergic blockade impaired the working memory. Therefore, we suggest that beta-adrenergic receptor activation is the main signaling system required for the retrieval of spatial memory. In addition, other modulatory interactions such as dopaminergic as well as MR systems are involved. This result points to specific roles of different modulatory systems during the retrieval of specific components of spatial memory. The data provide evidence for similar integrative interactions between different signaling systems during cellular memory processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.