Evidence map›Paper›PMID 17350934›Full record

ArticleArchaea (Vancouver, B.C.)2007

Gene decay in archaea.

M W J van Passel, C S Smillie, H Ochman

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Archaea (Vancouver, B.C.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Promoter propagation in prokaryotes.Nucleic acids research · 2012
    Article
  6. Translational recoding in archaea.Extremophiles : life under extreme conditions · 2012
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Deletional bias across the three domains of life.Genome biology and evolution · 2009
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M W J van PasselDepartment of Biochemistry and Molecular Biophysics, University of Arizona, 1007 East Lowell Street, Tucson, AZ 85721, USA. mvpassel@email.arizona.edu
C S Smillie
H Ochman
University of Arizona · US

Funding

Genome Erosion in Infectious MicroorganismsR01GM056120 · NIGMS · UNIVERSITY OF ROCHESTER · PI OCHMAN, HOWARD · 1997 to 2007
$1.3M
NIGMS NIH HHS GM56120NIGMS NIH HHS R01 GM056120
6 · The paper itself

Abstract

The gene-dense chromosomes of archaea and bacteria were long thought to be devoid of pseudogenes, but with the massive increase in available genome sequences, whole genome comparisons between closely related species have identified mutations that have rendered numerous genes inactive. Comparative analyses of sequenced archaeal genomes revealed numerous pseudogenes, which can constitute up to 8.6% of the annotated coding sequences in some genomes. The largest proportion of pseudogenes is created by gene truncations, followed by frameshift mutations. Within archaeal genomes, large numbers of pseudogenes contain more than one inactivating mutation, suggesting that pseudogenes are deleted from the genome more slowly in archaea than in bacteria. Although archaea seem to retain pseudogenes longer than do bacteria, most archaeal genomes have unique repertoires of pseudogenes.

Indexed as

Genes, ArchaealPseudogenesArchaeaBacteriaBase CompositionGene SilencingGenome, ArchaealPhylogeny

Identifiers

PMID17350934
PMCPMC2686384
OpenAlexW2152538475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.