Trial reportBMJ (Clinical research ed.)2007
Tonsillectomy versus watchful waiting in recurrent streptococcal pharyngitis in adults: randomised controlled trial.
Trial report in BMJ (Clinical research ed.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00136877 (Effect of Tonsillectomy on Preventing Recurrent Streptococcal Throat Infections), which is not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Tonsillectomy on Preventing Recurrent Streptococcal Throat Infections: A Randomized Controlled Trial
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Preventive Interventions to Reduce the Burden of Rheumatic Heart Disease in Populations at Risk: A Systematic Review.Journal of the American Heart Association · 2024Pooled it
- Clinical practice guideline: tonsillitis II. Surgical management.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Guideline
- Tonsillectomy or adenotonsillectomy versus non-surgical treatment for chronic/recurrent acute tonsillitis.The Cochrane database of systematic reviews · 2014Pooled it
- Tonsillitis.BMJ clinical evidence · 2014Pooled it
- Tonsillitis.BMJ clinical evidence · 2009Pooled it
- Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- Trial
- Short-term outcomes of tonsillectomy in adult patients with recurrent pharyngitis: a randomized controlled trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Trial
- Health-related quality of life and functional recovery outcomes following tonsillectomy among patients in Hail, Saudi Arabia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Trends and Practices in Tonsil Surgery-A National Survey for Otorhinolaryngologists.Laryngoscope investigative otolaryngology · 2025Article
- Peritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches.PloS one · 2025Article
- Treatment of recurrent acute tonsillitis-a systematic review and clinical practice recommendations.Frontiers in surgery · 2023Review
- The peritonsillar abscess and its management - is incision and drainage only a makeshift to the tonsillectomy or a permanent solution?Frontiers in medicine · 2023Article
- Article
- Article
- Effects of Osteopathic T9-T10 Vertebral Manipulation in Tonsillitis: A Randomized Clinical Trial.Healthcare (Basel, Switzerland) · 2021Article
- Article
- Article
- Ustekinumab-induced remission of recalcitrant guttate psoriasis: A case series.JAAD case reports · 2017Article
- Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the short term efficacy and safety of tonsillectomy for recurrent streptococcal pharyngitis in adults. Design Randomised controlled trial.
settingAcademic referral centre in Finland.
participants70 adults with documented recurrent episodes of streptococcal group A pharyngitis.
interventionInstant tonsillectomy (n=36) or remaining on waiting list as control (n=34).
main outcome measuresPercentage change in the risk of an episode of streptococcal pharyngitis at 90 days. Rates of all episodes of pharyngitis and days with symptoms and adverse effects.
resultsThe mean (SD) follow-up was 164 (63) days in the control group and 170 (12) days in the tonsillectomy group. At 90 days, streptococcal pharyngitis had recurred in 24% (8/34) in the control group and 3% (1/36) in the tonsillectomy group (difference 21%; 95% confidence interval 6% to 36%). The number needed to undergo tonsillectomy to prevent one recurrence was 5 (3 to 16). During the whole follow-up, the rates of other episodes of pharyngitis and days with throat pain and fever were significantly lower in the tonsillectomy group than in the control group. The most common morbidity related to tonsillectomy was postoperative throat pain (mean length 13 days, SD 4).
conclusionsAdults with a history of documented recurrent episodes of streptococcal pharyngitis were less likely to have further streptococcal or other throat infections or days with throat pain if they had their tonsils removed.
trial registrationClinical Trials NCT00136877.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.