ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2007
Transmission of spike trains at the retinogeniculate synapse.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 131 citations in OpenAlex.
- Awake alpha bursting emerges as the dynamic working state in a lateral geniculate thalamocortical cell model.PLoS computational biology · 2026Article
- Physiological basis of resolution acuity in vision.Nature communications · 2026Article
- Restoration of temporal separability between beta and movement ensemble co-firing with motor recovery.Neuron · 2025Article
- Impaired thalamic burst firing in fragile X syndrome.Cell reports · 2025Article
- Limited transmission of mixed convergent signals at the mouse retinogeniculate synapse.Neuron · 2025Article
- More than expected: extracellular waveforms and functional responses in monkey LGN.bioRxiv : the preprint server for biology · 2024Article
- Information-theoretic analyses of neural data to minimize the effect of researchers' assumptions in predictive coding studies.PLoS computational biology · 2023Article
- Stimulus contrast modulates burst activity in the lateral geniculate nucleus.Current research in neurobiology · 2023Article
- Interspike intervals within retinal spike bursts combinatorially encode multiple stimulus features.PLoS computational biology · 2020Article
- Physiological characterization of a rare subpopulation of doublet-spiking neurons in the ferret lateral geniculate nucleus.Journal of neurophysiology · 2020Article
- Temporal information loss in the macaque early visual system.PLoS biology · 2020Article
- The Augmentation of Retinogeniculate Communication during Thalamic Burst Mode.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Contrast gain control and retinogeniculate communication.The European journal of neuroscience · 2019Article
- Linkage between retinal ganglion cell density and the nonuniform spatial integration across the visual field.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- A novel mutual information estimator to measure spike train correlations in a model thalamocortical network.Journal of neurophysiology · 2018Article
- Receptive Field Properties of Koniocellular On/Off Neurons in the Lateral Geniculate Nucleus of Marmoset Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Autophosphorylated CaMKII Facilitates Spike Propagation in Rat Optic Nerve.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
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- Relationship between cortical state and spiking activity in the lateral geniculate nucleus of marmosets.The Journal of physiology · 2017Article
9 more citing papers are in PubMed but not listed here.
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Retinal spikes impinging on relay neurons in the lateral geniculate nucleus (LGN) generate synaptic potentials, which sometimes produce spikes sent to visual cortex. We examined how signal transmission is regulated in the macaque LGN by recording the retinal input to a single LGN neuron while stimulating the receptive field center with a naturalistic luminance sequence. After extracting the EPSPs, which are often partially merged with spike waveforms, we found that >95% of spikes were associated with an EPSP from a single retinal ganglion cell. Each spike within a "burst" train was generated by an EPSP, indicating that LGN bursts are inherited from retinal bursts. LGN neurons rarely fired unless at least two EPSPs summated within 40 ms. This facilitation in EPSP efficacy was followed by depression. If a spike was generated by the first EPSP in a pair, it did not alter the efficacy of the second EPSP. Hence, the timing of EPSPs arising from the primary retinal driver governs synaptic efficacy and provides the basis for successful retinogeniculate transmission.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.