Evidence map›Paper›PMID 17342244›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2007

Use of magnetic nanoparticles to visualize threadlike structures inside lymphatic vessels of rats.

Hyeon-Min Johng, Jung Sun Yoo, Tae-Jong Yoon, Hak-Soo Shin, Byung-Cheon Lee, Changhoon Lee, Jin-Kyu Lee, Kwang-Sup Soh

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Traditional Acupuncture Meets Modern Nanotechnology: Opportunities and Perspectives.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
  3. Article
  4. Ultrastructure of a Mobile Threadlike Tissue Floating in a Lymph Vessel.Evidence-based complementary and alternative medicine : eCAM · 2016
    Article
  5. Article
  6. Observation of the Primo Vessel Approaching the Axillary Lymph Node with the Fluorescent Dye, DiI.Evidence-based complementary and alternative medicine : eCAM · 2014
    Article
  7. Article
  8. A method for the observation of the primo vascular system in the thoracic duct of a rat.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  9. Article
  10. Composition of the extracellular matrix of lymphatic novel threadlike structures: is it keratin?Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  11. Review and Comment on the Relationship between Primo Vascular System and Meridians.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  12. Primo vascular system in the lymph vessel from the inguinal to the axillary nodes.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  13. Novel threadlike structures may be present on the large animal organ surface: evidence in Swine model.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  14. 50 years of bong-han theory and 10 years of primo vascular system.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hyeon-Min JohngBiomedical Physics Laboratory, FPRD School of Physics and Astronomy, Materials Chemistry Laboratory School of Chemistry and Research Institute of Basic Sciences Seoul National University, Seoul, Korea.
Jung Sun Yoo
Tae-Jong Yoon
Hak-Soo Shin
Byung-Cheon Lee
Changhoon Lee
Jin-Kyu Lee
Kwang-Sup Soh
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel application of fluorescent magnetic nanoparticles was made to visualize a new tissue which had not been detectable by using simple stereomicroscopes. This unfamiliar threadlike structure inside the lymphatic vessels of rats was demonstrated in vivo by injecting nanoparticles into lymph nodes and applying magnetic fields on the collecting lymph vessels so that the nanoparticles were taken up by the threadlike structures. Confocal laser scanning microscope images of cryosectioned specimens exhibited that the nanoparticles were absorbed more strongly by the threadlike structure than by the lymphatic vessels. Further examination using a transmission electron microscope revealed that the nanoparticles had been captured between the reticular fibers in the extracellular matrix of the threadlike structures. The emerging technology of nanoparticles not only allows the extremely elusive threadlike structures to be visualized but also is expected to provide a magnetically controllable means to investigate their physiological functions.

Identifiers

PMID17342244
PMCPMC1810370
OpenAlexW2130608128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.