ReviewCritical reviews in eukaryotic gene expression2007
Reflections on lineage potential of skeletal muscle satellite cells: do they sometimes go MAD?
Review in Critical reviews in eukaryotic gene expression, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Brown to White Fat Transition Overlap With Skeletal Muscle During Development of Larger Mammals: Is it a Coincidence?Journal of the Endocrine Society · 2022Review
- Isolation, Culture, and Immunostaining of Skeletal Muscle Myofibers from Wildtype and Nestin-GFP Mice as a Means to Analyze Satellite Cell.Methods in molecular biology (Clifton, N.J.) · 2017Article
- Murine muscle engineered from dermal precursors: an in vitro model for skeletal muscle generation, degeneration, and fatty infiltration.Tissue engineering. Part C, Methods · 2014Article
- Interaction between bone and muscle in older persons with mobility limitations.Current pharmaceutical design · 2014Review
- Developmental programming of fetal skeletal muscle and adipose tissue development.Journal of genomics · 2013Review
- Article
- Muscle-bound primordial stem cells give rise to myofiber-associated myogenic and non-myogenic progenitors.PloS one · 2011Article
- Reduced satellite cell numbers and myogenic capacity in aging can be alleviated by endurance exercise.PloS one · 2010Article
- Skeletal muscle growth defect in human growth hormone transgenic rat is accompanied by phenotypic changes in progenitor cells.Age (Dordrecht, Netherlands) · 2010Article
- Sarcopenia: etiology, clinical consequences, intervention, and assessment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010Review
- New multiple labelling method for improved satellite cell identification in human muscle: application to a cohort of power-lifters and sedentary men.Histochemistry and cell biology · 2009Article
- Defining the transcriptional signature of skeletal muscle stem cells.Journal of animal science · 2008Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Postnatal muscle growth and repair is supported by satellite cells--myogenic progenitors positioned between the myofiber basal lamina and plasma membrane. In adult muscles, satellite cells are quiescent but become activated and contribute differentiated progeny when myofiber repair is needed. The development of cells expressing osteogenic and adipogenic genes alongside myoblasts in myofiber cultures raised the hypothesis that satellite cells possess mesenchymal plasticity. Clonal studies of myofiber-associated cells further suggest that satellite cell myogeneity and diversion into Mesenchymal Alternative Differentiation (MAD) occur in vitro by a stochastic mechanism. However, in vivo this potential may be executed only when myogenic signals are impaired and the muscle tissue is compromised. Such a mechanism may contribute to the increased adiposity of aging muscles. Alternatively, it is possible that mesenchymal interstitial cells (sometimes co-isolated with myofibers), rather than satellite cells, account for the nonmyogenic cells observed in myogenic cultures. Herein, we first elaborate on the myogenic potential of satellite cells. We then introduce definitions of adult stem-cell unipotency, multipotency, and plasticity, as well as elaborate on recent studies that established the status of satellite cells as myogenic stem cells. Last, we highlight evidence in favor of satellite cell plasticity and emerging hurdles restraining this hypothesis.
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