ArticleJournal of assisted reproduction and genetics2007
Pregnancy outcome and live birth after IVF and ICSI according to embryo quality.
Article in Journal of assisted reproduction and genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07684339 (Assessing the Correlation Between Phospholipase C Zeta), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing the Correlation Between Phospholipase C Zeta (PLCZeta) Measurements and Semen Parameters
Who cites it
9 citing papers in PubMed.
- Article
- A Nomogram for Predicting the Risk of Twin and Preterm Births After Two Cleavage-Stage Embryo Transfer.International journal of general medicine · 2025Article
- Effects of Melatonin, GM-CSF, IGF-1, and LIF in Culture Media on Embryonic Development: Potential Benefits of Individualization.International journal of molecular sciences · 2024Review
- Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update.Frontiers in cell and developmental biology · 2020Review
- Article
- Factors that Influence The Occurrence of Multiple Pregnancies after Intracytoplasmic Injection Cycles with Two or Three Fresh Embryo Transfers.International journal of fertility & sterility · 2017Article
- Impact on ICSI outcomes of adding 24 h of in vitro culture before testicular sperm freezing: a retrospective study.Basic and clinical andrology · 2015Article
- Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- Early transcription from the maternal genome controlling blastomere integrity in mouse two-cell-stage embryos.American journal of physiology. Cell physiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe pregnancy outcome and the chances of birth were assessed according to embryo quality after IVF or ICSI.
methodsThe implantation rate (IR), the loss of gestational sacs rate (LGSR), and birth rate (BR) were determined according to the cleavage stage and the integrity of blastomeres after day-2 homogeneous embryo transfers (n = 1812).
resultsThe LGSR was higher after transfers of 2-3-cell or 5-6-cell embryos and was significantly increased when more than 20% of the embryo volume was fragmented in 4-cell embryos. After transfers of 4-cell embryos without fragmentation, the BR was significantly higher than the BR after transfers of 4-cell embryos with 1-20% fragmentation (16.6% vs 13.1%). The difference was the consequence of a higher IR (20.4% vs 17.3%) but also of a lower LGSR (18.9% vs 24.2%).
conclusionsNot only implantation and the ability to give a pregnancy, but also the capacity to give a live birth are dependent on the embryo quality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.