ArticleFunctional & integrative genomics2007
The human genome-wide distribution of DNA palindromes.
Article in Functional & integrative genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An updated overview of experimental and computational approaches to identify non-canonical DNA/RNA structures with emphasis on G-quadruplexes and R-loops.Briefings in bioinformatics · 2022Pooled it
- Mirror-synchronized asymmetric CRISPR nanoswitch for single-molecule profiling of multiple circRNAs in different stages of breast cancer.Nucleic acids research · 2025Article
- A 69.9-kb long inverted repeat increases genome instability in a strain ofNAR genomics and bioinformatics · 2025Article
- Article
- Palindromes in DNA-A Risk for Genome Stability and Implications in Cancer.International journal of molecular sciences · 2021Review
- Conventional PCR assisted single-component assembly of spherical nucleic acids for simple colorimetric detection of SARS-CoV-2.Sensors and actuators. B, Chemical · 2021Article
- A reference catalog of DNA palindromes in the human genome and their variations in 1000 Genomes.Human genome variation · 2020Article
- Regulation of gene expression by the action of a fungal lncRNA on a transactivator.RNA biology · 2020Article
- Symmetric exponential amplification reaction-based DNA nanomachine for the fluorescent detection of nucleic acids.RSC advances · 2019Article
- A pilot study on the prevalence of DNA palindromes in breast cancer genomes.BMC medical genomics · 2016Article
- A MATLAB-based tool for accurate detection of perfect overlapping and nested inverted repeats in DNA sequences.Bioinformatics (Oxford, England) · 2014Article
- detectIR: a novel program for detecting perfect and imperfect inverted repeats using complex numbers and vector calculation.PloS one · 2014Article
- Promoter analysis reveals globally differential regulation of human long non-coding RNA and protein-coding genes.PloS one · 2014Article
- Competitive superhelical transitions involving cruciform extrusion.Nucleic acids research · 2013Article
- A method to find palindromes in nucleic acid sequences.Bioinformation · 2013Article
- Compositional bias is a major determinant of the distribution pattern and abundance of palindromes in Drosophila melanogaster.Journal of molecular evolution · 2012Article
- Chromosomal translocations and palindromic AT-rich repeats.Current opinion in genetics & development · 2012Review
- Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA.The Journal of biological chemistry · 2012Article
- Species-specific typing of DNA based on palindrome frequency patterns.DNA research : an international journal for rapid publication of reports on genes and genomes · 2011Article
- The distribution of inverted repeat sequences in the Saccharomyces cerevisiae genome.Current genetics · 2010Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this work, we performed a systematic study of perfect and nonspacer palindromes present in human genomic DNA, and we investigated palindrome distribution over the entire human genome and over the functional regions such as the exon, intron, intergenic, and upstream regions (2,000 bp upstream from translational start site). We found that 24 palindrome-abundant intervals are mostly located on G-bands, which condense early, replicate late, and are relatively A+T rich. In general, palindromes are overrepresented in introns but underrepresented in exons. Upstream region has enriched palindrome distribution, where palindromes can serve as transcription factor binding sites. We created a Human DNA Palindrome Database (HPALDB) which is accessible at http://vhp.ntu.edu.sg/hpaldb . It contains 12,556,994 entries covering all palindromes in the human genome longer than 6 bp. Queries can be performed in different ways. Each entry in the database is linked to its location on NCBI's human chromosome Map Viewer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.