ReviewJournal of molecular medicine (Berlin, Germany)2007
Involvement of autophagy in viral infections: antiviral function and subversion by viruses.
Review in Journal of molecular medicine (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 94 citations in OpenAlex.
- Article
- Review
- A novel mechanistic study on inhibiting influenza A virus replication by a newly extracted polypeptide targeting host autophagy.Archives of microbiology · 2025Article
- Review
- Article
- A DNA Plasmid-Based Approach for Efficient Synthesis of Sacbrood Virus Infectious Clones within Host Cells.Viruses · 2023Article
- Natural and Engineered Resistance Mechanisms in Plants against Phytoviruses.Pathogens (Basel, Switzerland) · 2023Review
- Canine distemper virus N protein induces autophagy to facilitate viral replication.BMC veterinary research · 2023Article
- Coronavirus disease 2019 (COVID-19) update: From metabolic reprogramming to immunometabolism.Journal of medical virology · 2022Review
- Capsid protein from red-spotted grouper nervous necrosis virus induces incomplete autophagy by inactivating the HSP90ab1-AKT-MTOR pathway.Zoological research · 2022Article
- Antiviral Activity of Chrysin against Influenza Virus Replication via Inhibition of Autophagy.Viruses · 2021Article
- RNA editing in mesothelioma: a look forward.Open biology · 2020Review
- BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein.Autophagy · 2017Article
- Foot-and-mouth disease virus infection suppresses autophagy and NF-кB antiviral responses via degradation of ATG5-ATG12 by 3CCell death & disease · 2017Article
- The vesicular stomatitis virus matrix protein inhibits NF-κB activation in mouse L929 cells.Virology · 2016Article
- Viral (hepatitis C virus, hepatitis B virus, HIV) persistence and immune homeostasis.Immunology · 2014Review
- Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model.Journal of biomedical science · 2014Article
- Autophagy activated by Toxoplasma gondii infection in turn facilitates Toxoplasma gondii proliferation.Parasitology research · 2014Article
- Sustained autophagy contributes to measles virus infectivity.PLoS pathogens · 2013Article
- Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors.Virology journal · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autophagy is a cellular process involved in the degradation and turn-over of long-lived proteins and organelles, which can be subjected to suppression or further induction in response to different stimuli. According to its essential role in cellular homeostasis, autophagy has been implicated in several pathologies including cancer, neurodegeneration and myopathies. More recently, autophagy has been described as a mechanism of both innate and adaptive immunity against intracellular bacteria and viruses. In this context, autophagy has been proposed as a protective mechanism against viral infection by degrading the pathogens into autolysosomes. This is strengthened by the fact that several proteins involved in interferon (IFN) signalling pathways are linked to autophagy regulation. However, several viruses have evolved strategies to divert IFN-mediated pathways and autophagy to their own benefit. This review provides an overview of the autophagic process and its involvement in the infection by different viral pathogens and of the connections existing between autophagy and proteins involved in IFN signalling pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.