Evidence map›Paper›PMID 17338926›Full record

ReviewClinics in chest medicine2007

Pathology of pulmonary hypertension.

Rubin M Tuder, John C Marecki, Amy Richter, Iwona Fijalkowska, Sonia Flores

Abstract readReview
In one paragraph

Review in Clinics in chest medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Schistosomiasis-associated pulmonary arterial hypertension: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2020
    Pooled it
  2. The effect of phosphodiesterase-5 inhibitors on cerebral blood flow in humans: A systematic review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018
    Pooled it
  3. Trial
  4. Trial
  5. Article
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  7. Article
  8. The right time, the right cell: the potential for precision senotherapy in pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  9. Review
  10. The emerging role of integrin signaling in pulmonary vascular disease.American journal of physiology. Lung cellular and molecular physiology · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rubin M TuderDivision of Cardiopulmonary Pathology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Baltimore, MD 21217, USA. rtuder@jhmi.edu
John C Marecki
Amy Richter
Iwona Fijalkowska
Sonia Flores

Funding

VENTILATOR ASSOCIATED LUNG INJURY: MOLECULAR APPROACHESP50HL073994 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BROWER, ROY G. · 2003 to 2007
$21.3M
Vasculogenesis failure in neonatal pulmonary hypertensionP01HL066254 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI FRANKLIN, WILBUR A · 2001 to 2005
$5.8M
Pathobiology of HIV(SIV)-Induced Angioproliferative Pul*R01HL083491 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI FLORES, SONIA CASTRO · 2005 to 2009
$1.9M
RTP-801 in Cigarette Smoke-EmphysemaR01ES016285 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI TUDER, RUBIN M. · 2011 to 2015
$1.6M
Discovery of biomarkers of pulmonary hypertensionR21HL077805 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TUDER, RUBIN M · 2004 to 2005
$321k
NHLBI NIH HHS P01 HL066254NHLBI NIH HHS P01HL66254NHLBI NIH HHS P50 HL073994NHLBI NIH HHS R01 1HL083491NHLBI NIH HHS R01 HL083491NHLBI NIH HHS R21 HL077805NIEHS NIH HHS R01 ES016285
6 · The paper itself

Abstract

The secondary role of pathology in the present clinical management of pulmonary hypertension (PH) reflects to some extent the limitations of the current understanding of the disease. Ample room exists for the diagnostic translation of the pathobiologic studies, with the goal of improving the diagnostic and prognostic power of the pathologic assessment of pulmonary vascular remodeling. This article seeks to show the complementarities of the pathology and pathobiology of PH.

Indexed as

ApoptosisBone Morphogenetic Protein Receptors, Type IIBone Morphogenetic ProteinsCollagenEndothelial CellsEndotheliumFibroblastsGene Products, nefHumansHypertension, PulmonaryHypertrophyImmunohistochemistryInflammation MediatorsPulmonary ArteryVascular ResistanceBMPR2 protein, humanBone Morphogenetic Protein Receptors, Type IIBone Morphogenetic ProteinsCollagenGene Products, nefInflammation Mediators

Identifiers

PMID17338926
PMCPMC1924722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.