ReviewIndian journal of pediatrics2007
Dysfunction of innate immunity and associated pathology in neonates.
Review in Indian journal of pediatrics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Immunoaging - the effect of age on serum levels of NET biomarkers in men: a pilot study.International journal of occupational medicine and environmental health · 2023Article
- Clinical Symptoms, Pathogen Spectrum, Risk Factors and Antibiogram of Suspected Neonatal Sepsis Cases in Tertiary Care Hospital of Southern Part of Nepal: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2020Article
- The role of the season at admission in neonatal sepsis: a retrospective chart review of a 1-year data at University of Gondar comprehensive specialized hospital.BMC research notes · 2019Article
- Bacterial etiologic agents causing neonatal sepsis and associated risk factors in Gondar, Northwest Ethiopia.BMC pediatrics · 2017Article
- First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease.The Journal of infectious diseases · 2017Article
- Inflammatory mediators of systemic inflammation in neonatal sepsis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2013Article
- Very late onset infections in the neonatal intensive care unit.Early human development · 2012Article
- The changing spectrum of neonatal infectious disease.Journal of perinatology : official journal of the California Perinatal Association · 2010Review
- Perinatal nutrition and immunity to infection.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2010Review
- Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.Blood · 2009Article
- Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis.Journal of perinatology : official journal of the California Perinatal Association · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neutrophils and complement system are the critical elements of innate immunity mainly due to participation in the first line of defense against microorganisms by means of phagocytosis, lysis of bacteria and activation of naive B-lymphocytes. In this report we provide an overview of the up to date information regarding the neutrophil and complement system's functional ability in newborn infants in association with the maternal conditions that exist during the intrauterine stage, gestational age and post-neonatal pathology. The neonates' capacity to control the neutrophil and complement protein activation process has also been discussed because of the evidence that uncontrolled activation of these immune elements provides a significant contribution to the tissue damage and subsequent pathology. The authors are confident that despite the many unanswered questions this review updates their knowledge and points the need for further research to clarify the role of the age-associated dysfunction of neutrophils and complement system in the infection and inflammation related pathology of newborn infants.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.