ArticleSchizophrenia bulletin2007
Substance use and abuse in first-episode psychosis: prevalence before and after early intervention.
Article in Schizophrenia bulletin, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- Substance use disorder among people with first-episode psychosis: a systematic review of course and treatment.Psychiatric services (Washington, D.C.) · 2011Pooled it
- Trial
- How do psychedelics impact people with a history of non-affective psychosis? A qualitative study.Frontiers in psychiatry · 2025Article
- Psychotomimetic compensation versus sensitization.Pharmacology research & perspectives · 2024Review
- Perspectives of young adults diagnosed with early psychosis using coordinated specialty care in Texas on substance use and substance use interventions.Early intervention in psychiatry · 2024Article
- Correlates of substance use in a large naturalistic cohort of young people with early and emerging psychosis.Social psychiatry and psychiatric epidemiology · 2023Article
- Moderated Online Social Therapy for Carers of Early Psychosis Clients in Real-World Settings: Cluster Randomized Controlled Trial.JMIR mental health · 2023Article
- Insights About Cannabis and Psychosis Using Video Games for Young People With a First Episode of Psychosis, Particularly Those From Black Racialized Communities: Protocol for a Mixed Methods Study.JMIR research protocols · 2022Article
- A Retrospective Study of the Clinical Characteristics Associated with Alcohol and Cannabis use in Early Phase Psychosis.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2020Article
- Binge drinking: Prevalence, correlates, and expectancies of alcohol use among individuals with first-episode psychosis.Early intervention in psychiatry · 2019Article
- Cannabis acute use impacts symptoms and functionality in a cohort of antipsychotic naïve First Episode of Psychosis individuals.Schizophrenia research. Cognition · 2019Article
- Hazardous alcohol use in a sample of first episode psychosis patients in Singapore.BMC psychiatry · 2019Article
- First-episode psychosis and substance use in Nelson Mandela Bay: Findings from an acute mental health unit.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2019Article
- Early Substance Use Cessation Improves Cognition-10 Years Outcome in First-Episode Psychosis Patients.Frontiers in psychiatry · 2019Article
- Patterns of Management of Patients With Dual Disorder (Psychosis) in Italy: A Survey of Psychiatrists and Other Physicians Focusing on Clinical Practice.Frontiers in psychiatry · 2018Article
- The Effect of Substance Use on 10-Year Outcome in First-Episode Psychosis.Schizophrenia bulletin · 2017Article
- Psychosocial Interventions in Reducing Cannabis Use in Early Phase Psychosis: A Canadian Survey of Treatments Offered.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Article
- Psychotic disorders comorbid with attention-deficit hyperactivity disorder: an important knowledge gap.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2015Review
- Substance abuse and smoking among a Canadian cohort of first episode psychosis patients.Community mental health journal · 2013Article
- Gender differences in first episode psychotic mania.BMC psychiatry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledDespite the high prevalence of substance abuse among first-episode psychosis (FEP) populations, few studies examine whether early intervention (EI) improves substance abuse.
objectiveTo examine the prevalence and pattern of substance use and abuse among an FEP sample over 12 months.
methodsAll the participants were diagnosed with a first episode of a schizophrenia spectrum disorder. The participants were followed prospectively. The prevalence rates of substance use and abuse from this sample were compared before and after 12 months of EI services and were compared with rates observed in a sample from the general population.
resultsA total of 200 participants (80.0% males; mean age 24 years) entered the study: 183 participants completed all the assessments at baseline, 131 participants completed all the assessments at 12 months. At baseline, the findings showed similar prevalence rates between the FEP sample and the general sample for lifetime cannabis use (60% vs 55%, respectively) and hazardous alcohol use (26% vs 21%) but significantly different prevalence rates for lifetime hallucinogen (29% vs 15%; P < .001) and cocaine use (20% vs 14%; P < .001). At 12 months, the prevalence rates for drug abuse (P < .01), hazardous alcohol use (P < .01), and concurrent drug abuse and hazardous alcohol use (P < .05) were significantly lower than at baseline.
conclusionSubstance use and abuse decreased significantly after 12 months of EI services; EI services may be able to detect and to reduce substance use among FEP patients before it becomes a more serious disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.