Evidence map›Paper›PMID 17337639›Full record

ArticleEukaryotic cell2007

Expression and interstrain variability of the YPS3 gene of Histoplasma capsulatum.

Megan L Bohse, Jon P Woods

Open access · diamondAbstract read
In one paragraph

Article in Eukaryotic cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Comparative Proteomic Analysis ofFrontiers in microbiology · 2021
    Article
  6. Review
  7. Immunoproteomics Reveals Pathogen's Antigens Involved inFrontiers in cellular and infection microbiology · 2020
    Article
  8. Dimorphism and Dissemination ofThe American journal of tropical medicine and hygiene · 2019
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. The spectrum of fungi that infects humans.Cold Spring Harbor perspectives in medicine · 2014
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Surface architecture of histoplasma capsulatum.Frontiers in microbiology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Megan L BohseDepartment of Medical Microbiology and Immunology, 420 SMI, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI 53706, USA.
Jon P Woods
University of Wisconsin–Madison · US

Funding

Microbial Pathogenesis &Host Responses Training ProgramT32AI055397 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2003 to 2024
$5.5M
T CELL RECEPTOR USAGE IN PULMONARY HISTOPLASMOSISR37AI042747 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 1997 to 2006
$2.2M
MOLECULAR PATHOGENESIS OF PULMONARY HISTOPLASMOSISR01HL055949 · NHLBI · UNIVERSITY OF WISCONSIN MADISON · PI WOODS, JON P. · 1995 to 2004
$1.7M
Histoplasma capsulatum Iron Acquisition and UtilizationR01AI052303 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WOODS, JON P. · 2002 to 2006
$1.5M
NHLBI NIH HHS R01 HL055949NHLBI NIH HHS R01 HL55949NIAID NIH HHS R01 AI052303NIAID NIH HHS R01 AI52303NIAID NIH HHS R37 AI042747NIAID NIH HHS R37 AI42747NIAID NIH HHS T32 AI055397
6 · The paper itself

Abstract

The YPS3 locus of the dimorphic fungus Histoplasma capsulatum encodes a secreted and surface-localized protein specific to the pathogenic yeast phase. In this study we examined this locus in 32 H. capsulatum strains and variants. Although protein production is limited to a select group of strains, the North American restriction fragment length polymorphism class 2/NAm 2 isolates, the locus was present in all the strains we examined. The YPS3 gene is well conserved in its 5' and 3' regions but displays an intragenic hypervariable region of tandem repeats that fluctuates in size between strains. This feature is similar to that seen with genes encoding several cell surface proteins in other fungi.

Indexed as

Genetic VariationAmino Acid SequenceBase SequenceFungal ProteinsGene Expression Regulation, FungalGenes, FungalHistoplasmaMolecular Sequence DataOpen Reading FramesSequence Analysis, DNAFungal Proteins

Identifiers

PMID17337639
PMCPMC1865658
OpenAlexW2116553265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.