ReviewMolecular imaging and biology
Functional imaging of cerebral blood flow and glucose metabolism in Parkinson's disease and Huntington's disease.
Review in Molecular imaging and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- What are the neural correlates of meta-cognition and anosognosia in Alzheimer's disease? A systematic review.Neurobiology of aging · 2020Pooled it
- Mind-Body Interventions as Modulators of Neural Connectivity and Cognition in Individuals at Risk for Alzheimer's Disease: A Systematic Review.Annals of neurosciences · 2026Review
- Positron Emission Tomography Imaging in Clinical Trials for Parkinson's Disease: Applications of Metabolic Brain Network Approach.Movement disorders : official journal of the Movement Disorder Society · 2025Review
- Functional brain networks in the evaluation of patients with neurodegenerative disorders.Nature reviews. Neurology · 2023Review
- Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation.Disease models & mechanisms · 2022Article
- Impaired response of cerebral oxygen metabolism to visual stimulation in Huntington's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors.Magnetic resonance in medicine · 2018Article
- Association Between Motor Symptoms and Brain Metabolism in Early Huntington Disease.JAMA neurology · 2017Article
- Parkinson's disease-related network topographies characterized with resting state functional MRI.Human brain mapping · 2017Article
- Glucose metabolism-weighted imaging with chemical exchange-sensitive MRI of 2-deoxyglucose (2DG) in brain: Sensitivity and biological sources.NeuroImage · 2016Article
- Molecular imaging of movement disorders.World journal of radiology · 2016Review
- Brain network markers of abnormal cerebral glucose metabolism and blood flow in Parkinson's disease.Neuroscience bulletin · 2014Review
- The effects of methylphenidate on resting-state striatal, thalamic and global functional connectivity in healthy adults.The international journal of neuropsychopharmacology · 2014Article
- IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice.Molecular neurobiology · 2014Article
- Vessel-specific quantification of blood oxygenation with T2-relaxation-under-phase-contrast MRI.Magnetic resonance in medicine · 2014Article
- Elevated arteriolar cerebral blood volume in prodromal Huntington's disease.Movement disorders : official journal of the Movement Disorder Society · 2014Article
- Identification of disease-related spatial covariance patterns using neuroimaging data.Journal of visualized experiments : JoVE · 2013Article
- Metabolic brain networks in translational neurology: concepts and applications.Annals of neurology · 2012Review
- Monitoring Huntington's disease progression through preclinical and early stages.Neurodegenerative disease management · 2012Article
- Functional brain networks in movement disorders: recent advances.Current opinion in neurology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Brain imaging of cerebral blood flow and glucose metabolism has been playing key roles in describing pathophysiology of Parkinson's disease (PD) and Huntington's disease (HD), respectively. Many biomarkers have been developed in recent years to investigate the abnormality in molecular substrate, track the time course of disease progression, and evaluate the efficacy of novel experimental therapeutics. A growing body of literature has emerged on neurobiology of these two movement disorders in resting states and in response to brain activation tasks. In this paper, we review the latest applications of these approaches in patients and normal volunteers at rest conditions. The discussions focus on brain mapping studies with univariate and multivariate statistical analyses on a voxel basis. In particular, we present data to validate the reproducibility and reliability of unique spatial covariance patterns related with PD and HD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.