ArticleCurrent microbiology2007
Genetic and comparative transcriptome analysis of bromodomain factor 1 in the salt stress response of Saccharomyces cerevisiae.
Article in Current microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- IAT4, a New Indolamine N-Acetyltransferase in Saccharomyces cerevisiae Involved in Melatonin Biosynthesis.Journal of pineal research · 2025Article
- Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1.Current genetics · 2023Article
- Selective BET bromodomain inhibition as an antifungal therapeutic strategy.Nature communications · 2017Article
- HAL2 overexpression induces iron acquisition in bdf1Δ cells and enhances their salt resistance.Current genetics · 2017Article
- Differences between flocculating yeast and regular industrial yeast in transcription and metabolite profiling during ethanol fermentation.Saudi journal of biological sciences · 2017Article
- Quantitative proteomic comparison of stationary/G0 phase cells and tetrads in budding yeast.Scientific reports · 2016Article
- Depletion of yeast PDK1 orthologs triggers a stress-like transcriptional response.BMC genomics · 2015Article
- The yeast BDF1 regulates endocytosis via LSP1 under salt stress.Current microbiology · 2015Article
- The capacity ofFungal biology and biotechnology · 2014Article
- Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast.Genes & development · 2013Article
- Article
- Improvement of L-arabinose fermentation by modifying the metabolic pathway and transport in Saccharomyces cerevisiae.BioMed research international · 2013Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Saccharomyces cerevisiae BDF1 gene, which encodes a bromodomain-containing transcription factor, was previously isolated by transposon mutugenesis in a screen for salt-sensitive mutants. However, the salt stress response mechanism regulated by bromodomain transcription factor 1 protein (Bdf1p) remains poorly understood. In this report, genetic analysis indicated that the salt sensitivity of the BDF1 deletion mutant was suppressed by increased gene dosage of its homologous gene BDF2. Furthermore, comparative transcriptome analysis revealed that the differences in transcriptional response between the wild type and the bdf1Delta mutant in the presence of salt stress (0.6 mol/L NaCl, 45 min) were mainly related to cell-wall biosynthesis, the mitochondria, and several unknown genes. Our results provided further information about the regulatory mechanism involved in the salt stress response and adds new insight for understanding the biological functional of bromdomain-containing proteins in cellular processes.
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