Evidence map›Paper›PMID 17334784›Full record

ArticleEuropean journal of pediatrics2008

Varicella vaccination in Europe: are we ready for a universal childhood programme?

Nitu Sengupta, Robert Booy, H J Schmitt, Heikki Peltola, Pierre Van-Damme, R Fabian Schumacher, Magda Campins, Carlos Rodrigo, Terho Heikkinen, Jane Seward and 6 more

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Article in European journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Vaccines for preventing herpes zoster in older adults.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Successes and challenges in varicella vaccine.Therapeutic advances in vaccines · 2014
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Should the UK introduce varicella vaccine?Archives of disease in childhood · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nitu SenguptaCentre for Child Health, Royal London Hospital, 38 New Road, Whitechapel, London, E1 2AX, UK. n.sengupta@qmul.ac.uk
Robert Booy
H J Schmitt
Heikki Peltola
Pierre Van-Damme
R Fabian Schumacher
Magda Campins
Carlos Rodrigo
Terho Heikkinen
Jane Seward
Aisha Jumaan
Adam Finn
Per Olcén
Nancy Thiry
Catherine Weil-Olivier
Judith Breuer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safe and effective vaccines against varicella zoster virus (VZV), the aetiological agent of varicella and shingles, have been available in Europe for the last 5-10 years. The USA has had a universal childhood vaccination policy since 1995 and this has resulted in a dramatic decrease in the incidence, morbidity and mortality related to varicella. The economic and medical burden of VZV has led to discussions regarding both the desirability and feasibility of a similar routine immunisation policy for all European children. This article examines the epidemiology of varicella in Europe and how the data emerging from the USA can be used to achieve adequate prevention of the disease. It looks into the current evidence of the health economic evaluation of universal varicella vaccination and explores the concerns surrounding such a policy, including the postulated impact on the incidence of zoster. In conclusion, the Society of Independent European Vaccination Experts (SIEVE) recommends that the immunisation of susceptible adolescents needs to be urgently implemented, in addition to the current recommendations targeting high-risk patients, their close contacts with a negative history of varicella and seronegative health-care workers. A universal policy, optimally incorporating a two-dose schedule, will be needed to finally reduce the burden of disease of varicella from a societal point of view. The SIEVE recommends the implementation of such a policy as soon as financially and practically possible.

Indexed as

Chickenpox VaccineAdolescentChickenpoxChildChild, PreschoolEuropeHealth PolicyHospitalizationHumansImmunization ProgramsInfantModels, TheoreticalChickenpox Vaccine

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.