Evidence map›Paper›PMID 17334501›Full record

ReviewThrombosis and haemostasis2007

Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis.

Erhard Hofer, Bernhard Schweighofer

Open access · greenAbstract readReview
In one paragraph

Review in Thrombosis and haemostasis, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
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  6. Review
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  8. Review
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  10. Article
  11. Tumor angiogenesis: causes, consequences, challenges and opportunities.Cellular and molecular life sciences : CMLS · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Review
  18. Review
  19. Review
  20. Macrophages under pressure: the role of macrophage polarization in hypertension.Translational research : the journal of laboratory and clinical medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Erhard HoferDepartment of Vascular Biology and Thrombosis Research, Center for Biomolecular Medicine and Pharmacology, Medical University of Vienna, Vienna, Austria. erhard.hofer@meduniwien.ac.at
Bernhard Schweighofer
Medical University of Vienna · AT

Funding

Austrian Science Fund FWF S 9403
6 · The paper itself

Abstract

New vessel formation during development and in the adult is triggered by concerted signals of largely endothelial-specific receptors for ligands of the VEGF, angiopoietin and ephrin families. The signals and genes induced by these receptors operate in the context of additional signals transduced by non-endothelial specific growth factor receptors, inflammatory cytokine receptors as well as adhesion molecules. We summarize here available data on characteristic signaling of the VEGF receptor-2 and the current state of knowledge regarding the additional different receptor tyrosine kinases of the VEGF, Tie and Ephrin receptor families. Furthermore, the potential cross-talk with signals induced by other growth factors and inflammatory cytokines as well as the modulation by VE-cadherin is discussed.

Indexed as

Neovascularization, PhysiologicSignal TransductionAngiopoietinsAnimalsAntigens, CDCadherin 5CadherinsCytokinesEndothelial CellsEphrinsHumansReceptor Cross-TalkReceptors, Eph FamilyReceptors, Growth FactorReceptors, TIEVascular Endothelial Growth Factor Receptor-2AngiopoietinsAntigens, CDCadherin 5CadherinsCytokinesEphrinsReceptors, Eph FamilyReceptors, Growth FactorReceptors, TIEVascular Endothelial Growth Factor Receptor-2Vascular Endothelial Growth Factors

Identifiers

PMID17334501
PMCPMC2879321
OpenAlexW2095445691

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.