Evidence map›Paper›PMID 17333410›Full record

ReviewJournal of clinical immunology2007

gammadelta T lymphocytes-selectable cells within the innate system?

Willi K Born, Niyun Jin, M Kemal Aydintug, J M Wands, Jena D French, Christina L Roark, Rebecca L O'Brien

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of clinical immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Gut-derived immune cells and the gut-lung axis in ARDS.Critical care (London, England) · 2024
    Review
  4. Article
  5. Article
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  7. Review
  8. Review
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  11. Review
  12. γδ T cells protect against LPS-induced lung injury.Journal of leukocyte biology · 2016
    Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Willi K BornDepartment of Immunology at National Jewish Medical and Research Center, 1400 Jackson Street, Denver, Colorado 80206, USA. bornw@njc.org
Niyun Jin
M Kemal Aydintug
J M Wands
Jena D French
Christina L Roark
Rebecca L O'Brien
University of Colorado Denver · USNational Jewish Health · US

Funding

RESPONSE OF GAMMA/DELTA T CELLS TO CARDIOLIPIN AND DNAR01AI040611 · NIAID · NATIONAL JEWISH HEALTH · PI BORN, WILLI K · 1997 to 2004
$1.3M
NIAID NIH HHS AI40611PHS HHS RL65410
6 · The paper itself

Abstract

Lymphocytes expressing gammadelta T cell receptors (TCR) constitute an entire system of functionally specialized subsets that have been implicated in the regulation of immune responses, including responses to pathogens and allergens, and in tissue repair. The gammadelta TCRs share structural features with adaptive receptors and peripheral selection of gammadelta T cells occurs. Nevertheless, their specificities may be primarily directed at self-determinants, and the responses of gammadelta T cells exhibit innate characteristics. Continuous cross talk between gammadelta T cells and myeloid cells is evident in histological studies and in in vitro co-culture experiments, suggesting that gammadelta T cells play a functional role as an integral component of the innate immune system.

Indexed as

Immunity, InnateAnimalsHumansLymphocyte ActivationReceptors, Antigen, T-Cell, gamma-deltaT-Lymphocyte SubsetsReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID17333410
OpenAlexW2018700395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.