ArticleJournal of neuro-oncology2007
Embryonal tumor with abundant neuropil and true rosettes (ETANTR): report of a case with prominent neurocytic differentiation.
Article in Journal of neuro-oncology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 51 citations in OpenAlex.
- Clinicopathological and prognostic insights into Embryonal Tumors with Multilayered Rosettes (ETMRs).Diagnostic pathology · 2026Article
- Case report: Infratentorial Embryonal Tumor with Abundant Neuropil and True Rosettes (ETANTR) in an 8-month-old Maine Coon.Frontiers in veterinary science · 2022Article
- Embryonal tumor with multilayered rosettes in a teenager.Autopsy & case reports · 2022Article
- ETMR: a tumor entity in its infancy.Acta neuropathologica · 2020Review
- Medulloepithelioma with heterologous osteoid component: a case report and review of literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Review
- CT and Multimodal MR Imaging Features of Embryonal Tumors with Multilayered Rosettes in Children.AJNR. American journal of neuroradiology · 2019Article
- Radiation for ETMR: Literature review and case series of patients treated with proton therapy.Clinical and translational radiation oncology · 2019Article
- Rare Primary Central Nervous System Tumors Encountered in Pediatrics.Journal of child neurology · 2016Review
- Evaluation of the good tumor response of embryonal tumor with abundant neuropil and true rosettes (ETANTR).Journal of neuro-oncology · 2016Review
- Systematic comparison of MRI findings in pediatric ependymoblastoma with ependymoma and CNS primitive neuroectodermal tumor not otherwise specified.Neuro-oncology · 2015Article
- Long-term survival in a case of ETANTR with histological features of neuronal maturation after therapy.Virchows Archiv : an international journal of pathology · 2015Article
- The role of CD133+ cells in a recurrent embryonal tumor with abundant neuropil and true rosettes (ETANTR).Brain pathology (Zurich, Switzerland) · 2014Article
- Embryonal tumor with abundant neuropil and true rosettes: an autopsy case-based update and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Review
- Loss of INI1 protein expression defines a subgroup of aggressive central nervous system primitive neuroectodermal tumors.Brain pathology (Zurich, Switzerland) · 2013Article
- Analysis of chromosome 19q13.42 amplification in embryonal brain tumors with ependymoblastic multilayered rosettes.Brain pathology (Zurich, Switzerland) · 2012Article
- A 3-year- old girl with altered mental status, gait difficulty, and vomiting.Brain pathology (Zurich, Switzerland) · 2011Article
- Molecular diagnostics of CNS embryonal tumors.Acta neuropathologica · 2010Review
- Embryonal tumor with abundant neuropil and true rosettes (ETANTR): a new distinctive variety of pediatric PNET: a case-based update.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010Article
- Central nervous system primitive neuroectodermal tumors: a clinicopathologic and genetic study of 33 cases.Brain pathology (Zurich, Switzerland) · 2010Article
- Ependymoblastoma: dear, damned, distracting diagnosis, farewell!*.Brain pathology (Zurich, Switzerland) · 2010Article
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of a 2 year-old boy who initially presented with macrocephaly and severe global developmental delay. Imaging revealed a large left temporo-parietal mass that was lobulated, calcified, focally enhancing and partially cystic. A second surgery was required for tumor recurrence approximately one year later, and tissue from that resection proved to be diagnostic for an embryonal tumor with abundant neuropil and true rosettes (ETANTR). Only 12 cases of this rare pediatric embryonal tumor have been previously documented, and as of 2000, the WHO has not recognized ETANTR as a distinct entity (Kleihues P, Cavenee WK (2000) International agency for research on cancer: pathology and genetics of tumors of the nervous system. IARC Press, Lyon). As opposed to prior cases, our patient's tumor exhibited extensive neurocytic elements. Two recently described cases were examined via fluorescence in situ hybridization (FISH), with one demonstrating isochromosome 17q (i17q) and the second exhibiting polysomies of chromosomes 2, 8, 17 and 22 (Fuller C, Fouladi M, Gajjar A, Dalton J, Sanford RA, Helton KJ (2000) Am J Clin Pathol 126: 277-283). Via FISH analysis, we found normal dosages of chromosomes 2, 8 and 17. Our case expands the histopathologic spectrum of ETANTR, illustrating marked neuronal differentiation towards neurocytes. The lack of common PNET-associated FISH abnormalities in this case adds to the limited cytogenetic genetic data on this rare pediatric embryonal neoplasm.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.