ArticlePloS one2007
On the origin of the functional architecture of the cortex.
Article in PloS one, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- An illusion predicted by V1 population activity implicates cortical topography in shape perception.Nature neuroscience · 2013Trial
- Orientation decoding depends on maps, not columns.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Trial
- Functional Clusters for Shape, Texture, and Motion Encoding in Macaque V2.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Functional clusters for shape, texture, and motion encoding in macaque V2.bioRxiv : the preprint server for biology · 2025Article
- High-Density Recording Reveals Sparse Clusters (But Not Columns) for Shape and Texture Encoding in Macaque V4.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Luminance invariant encoding in mouse primary visual cortex.Cell reports · 2025Article
- Hue and orientation pinwheels in macaque area V4.Journal of neurophysiology · 2024Article
- Common modular architecture across diverse cortical areas in early development.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- High-density recording reveals sparse clusters (but not columns) for shape and texture encoding in macaque V4.bioRxiv : the preprint server for biology · 2023Article
- Thalamocortical boutons cluster by ON/OFF responses in mouse primary visual cortex.Journal of neurophysiology · 2023Article
- ON/OFF domains shape receptive field structure in mouse visual cortex.Nature communications · 2022Article
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- Spontaneous Retinal Waves Can Generate Long-Range Horizontal Connectivity in Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Interlayer Repulsion of Retinal Ganglion Cell Mosaics Regulates Spatial Organization of Functional Maps in the Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Topographic Independent Component Analysis reveals random scrambling of orientation in visual space.PloS one · 2017Article
- Orientation Selectivity from Very Sparse LGN Inputs in a Comprehensive Model of Macaque V1 Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Spatial clustering of tuning in mouse primary visual cortex.Nature communications · 2016Article
- Random Wiring, Ganglion Cell Mosaics, and the Functional Architecture of the Visual Cortex.PLoS computational biology · 2015Article
- Statistics and geometry of orientation selectivity in primary visual cortex.Biological cybernetics · 2014Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
The basic structure of receptive fields and functional maps in primary visual cortex is established without exposure to normal sensory experience and before the onset of the critical period. How the brain wires these circuits in the early stages of development remains unknown. Possible explanations include activity-dependent mechanisms driven by spontaneous activity in the retina and thalamus, and molecular guidance orchestrating thalamo-cortical connections on a fine spatial scale. Here I propose an alternative hypothesis: the blueprint for receptive fields, feature maps, and their inter-relationships may reside in the layout of the retinal ganglion cell mosaics along with a simple statistical connectivity scheme dictating the wiring between thalamus and cortex. The model is shown to account for a number of experimental findings, including the relationship between retinotopy, orientation maps, spatial frequency maps and cytochrome oxidase patches. The theory's simplicity, explanatory and predictive power makes it a serious candidate for the origin of the functional architecture of primary visual cortex.
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