ArticleJournal of the American Medical Informatics Association : JAMIA
Computer-based insulin infusion protocol improves glycemia control over manual protocol.
Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Tight glycemic control and computerized decision-support systems: a systematic review.Intensive care medicine · 2009Pooled it
- A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset.Critical care (London, England) · 2008Pooled it
- Clinical and economic impact of digital dashboards on hospital inpatient care: a systematic review.JAMIA open · 2025Review
- A Retrospective Cohort Analysis of Two Computerized Insulin Infusion Protocols.Journal of diabetes science and technology · 2023Article
- Diabetes Technology in the Inpatient Setting for Management of Hyperglycemia.Endocrinology and metabolism clinics of North America · 2020Review
- An Electronic Health Record-Integrated Computerized Intravenous Insulin Infusion Protocol: Clinical Outcomes andDiabetes & metabolism journal · 2020Article
- Hypoglycemia Prevention by Algorithm Design During Intravenous Insulin Infusion.Current diabetes reports · 2018Review
- Strict glycemic control to prevent surgical site infections in gastroenterological surgery.Annals of gastroenterological surgery · 2017Review
- Intraoperative blood glucose management: impact of a real-time decision support system on adherence to institutional protocol.Journal of clinical monitoring and computing · 2016Article
- Space GlucoseControl system for blood glucose control in intensive care patients--a European multicentre observational study.BMC anesthesiology · 2016Observational
- Population-Specific Models of Glycemic Control in Intensive Care: Towards a Simulation-Based Methodology for Protocol Optimization.Proceedings of the ... American Control Conference. American Control Conference · 2015Article
- The implementation of an Intensive Care Information System allows shortening the ICU length of stay.Journal of clinical monitoring and computing · 2015Observational
- Continuous glucose control in the ICU: report of a 2013 round table meeting.Critical care (London, England) · 2014Review
- Inpatient management of women with gestational and pregestational diabetes in pregnancy.Current diabetes reports · 2014Review
- The future is now: software-guided intensive insulin therapy in the critically ill.Journal of diabetes science and technology · 2013Review
- Duration of time on intensive insulin therapy predicts severe hypoglycemia in the surgically critically ill population.World journal of surgery · 2012Article
- Barriers and facilitators to the use of computer-based intensive insulin therapy.International journal of medical informatics · 2011Article
- Analyses of longitudinal, hospital clinical laboratory data with application to blood glucose concentrations.Statistics in medicine · 2011Article
- Provision of balanced nutrition protects against hypoglycemia in the critically ill surgical patient.JPEN. Journal of parenteral and enteral nutrition · 2011Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveHyperglycemia worsens clinical outcomes in critically ill patients. Precise glycemia control using intravenous insulin improves outcomes. To determine if we could improve glycemia control over a previous paper-based, manual protocol, authors implemented, in a surgical intensive care unit (SICU), an intravenous insulin protocol integrated into a care provider order entry (CPOE) system.
designRetrospective before-after study of consecutive adult patients admitted to a SICU during pre (manual protocol, 32 days) and post (computer-based protocol, 49 days) periods. MEASUREMENTS: Percentage of glucose readings in ideal range of 70-109 mg/dl, and minutes spent in ideal range of control during the first 5 days of SICU stay.
resultsThe computer-based protocol reduced time from first glucose measurement to initiation of insulin protocol, improved the percentage of all SICU glucose readings in the ideal range, and improved control in patients on IV insulin for > or =24 hours. Hypoglycemia (<40 mg/dl) was rare in both groups.
conclusionThe CPOE-based intravenous insulin protocol improved glycemia control in SICU patients compared to a previous manual protocol, and reduced time to insulin therapy initiation. Integrating a computer-based insulin protocol into a CPOE system achieved efficient, safe, and effective glycemia control in SICU patients.
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Registered trials
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