ArticleJournal of clinical microbiology2007
Genotyping of Candida orthopsilosis clinical isolates by amplification fragment length polymorphism reveals genetic diversity among independent isolates and strain maintenance within patients.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 114 citations in OpenAlex.
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- The first established microsatellite markers to distinguishJournal of clinical microbiology · 2023Article
- Analysis of the microbial content of probiotic products commercialized worldwide and survivability in conditions mimicking the human gut environment.Frontiers in microbiology · 2023Article
- A case ofClinical case reports · 2023Article
- Microbiological Quality and Resistance to an Artificial Gut Environment of Two Probiotic Formulations.Foods (Basel, Switzerland) · 2021Article
- Genome-Wide Analyses of Repeat-Induced Point Mutations in the Ascomycota.Frontiers in microbiology · 2020Article
- Recent trends in molecular diagnostics of yeast infections: from PCR to NGS.FEMS microbiology reviews · 2019Review
- Molecular Identification, Genotypic Diversity, Antifungal Susceptibility, and Clinical Outcomes of Infections Caused by Clinically Underrated Yeasts,Frontiers in cellular and infection microbiology · 2019Article
- Article
- Design and validation of a multiplex PCR protocol for microsatellite typing of Candida parapsilosis sensu stricto isolates.BMC genomics · 2018Article
- Microsatellite genotyping of clinical Candida parapsilosis isolates.Current medical mycology · 2017Article
- Comparison of four molecular approaches to identify Candida parapsilosis complex species.Memorias do Instituto Oswaldo Cruz · 2017Article
- Caspofungin-Non-SusceptibleIranian journal of public health · 2017Article
- Multiple Origins of the Pathogenic Yeast Candida orthopsilosis by Separate Hybridizations between Two Parental Species.PLoS genetics · 2016Article
- Exploring the In Vitro Resistance of Candida parapsilosis to Echinocandins.Mycopathologia · 2016Article
- Species Distribution, Virulence Factors, and Antifungal Susceptibility Among Candida parapsilosis Complex Isolates Recovered from Clinical Specimens.Mycopathologia · 2015Article
- Multicenter evaluation of Candida QuickFISH BC for identification of Candida species directly from blood culture bottles.Journal of clinical microbiology · 2015Article
- A case of Candida orthopsilosis associated septic arthritis in a patient with Systemic Lupus Erythematosus (SLE).Medical mycology case reports · 2015Article
- Genetic diversity of medically important and emerging Candida species causing invasive infection.BMC infectious diseases · 2015Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida parapsilosis former groups II and III have recently been established as independent species named C. orthopsilosis and C. metapsilosis, respectively. In this report, 400 isolates (290 patients) previously classified as C. parapsilosis by conventional laboratory tests were screened by BanI digestion profile analysis of the secondary alcohol dehydrogenase gene fragment and by amplification fragment length polymorphism (AFLP). Thirty-three strains collected from 13 patients were identified as C. orthopsilosis, thus giving the first retrospective evidence that C. orthopsilosis was responsible for 4.5% of the infections/colonization attributed to C. parapsilosis. AFLP was proven to unambiguously identify C. orthopsilosis at the species level and efficiently delineate intraspecific genetic relatedness. A high percentage of polymorphic AFLP bands was observed for independent isolates collected from each patient. Statistical analysis of the pairwise genetic distances and bootstrapping revealed that clonal reproduction and recombination both contribute to C. orthopsilosis genetic population structure. AFLP patterns of sequential isolates obtained from two patients demonstrated that a successful strain colonization within the same patient occurred, as revealed by strain maintenance in various body sites. No association between AFLP markers and drug resistance was observed, and none of the clinical C. orthopsilosis isolates were found to produce biofilm in vitro.
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