ArticleMolecular and cellular biology1992
Activation of a system for the joining of nonhomologous DNA ends during Xenopus egg maturation.
Article in Molecular and cellular biology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- DNA repair in primordial follicle oocytes following cisplatin treatment.Journal of assisted reproduction and genetics · 2021Article
- Review
- The capacity of oocytes for DNA repair.Cellular and molecular life sciences : CMLS · 2018Review
- Initiation of V(D)J recombination in zebrafish (Danio rerio) ovaries.Molecular immunology · 2007Article
- Restriction enzymes increase efficiencies of illegitimate DNA integration but decrease homologous integration in mammalian cells.Nucleic acids research · 2001Article
- DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae.Genetics · 2000Article
- Ku-dependent nonhomologous DNA end joining in Xenopus egg extracts.Molecular and cellular biology · 1999Article
- In vitro and in vivo reconstitution and stability of vertebrate chromosome ends.Nucleic acids research · 1998Article
- Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions.Nucleic acids research · 1997Article
- Regulation by phosphorylation of Xenopus laevis poly(ADP-ribose) polymerase enzyme activity during oocyte maturation.The Biochemical journal · 1997Article
- The RAD5 gene product is involved in the avoidance of non-homologous end-joining of DNA double strand breaks in the yeast Saccharomyces cerevisiae.Nucleic acids research · 1997Article
- Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae.Molecular and cellular biology · 1996Article
- A modified single-strand annealing model best explains the joining of DNA double-strand breaks mammalian cells and cell extracts.Nucleic acids research · 1995Article
- Repair of heteroduplex DNA in Xenopus laevis oocytes.Genetics · 1994Article
- Nonhomologous DNA end joining in Schizosaccharomyces pombe efficiently eliminates DNA double-strand-breaks from haploid sequences.Nucleic acids research · 1994Article
- Illegitimate recombination in Xenopus: characterization of end-joined junctions.Nucleic acids research · 1994Article
- Homologous and illegitimate recombination in developing Xenopus oocytes and eggs.Molecular and cellular biology · 1993Article
- Intermediates in extrachromosomal homologous recombination in Xenopus laevis oocytes: characterization by electron microscopy.The EMBO journal · 1993Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mature Xenopus laevis eggs provide an elementary reaction system of illegitimate recombination which efficiently joins nonhomologous DNA ends (P. Pfeiffer and W. Vielmetter, Nucleic Acids Res. 16:907-924, 1988). Here we show that stage VI oocytes, known to express a system for homologous recombination (D. Carroll, Proc. Natl. Acad. Sci. USA 80:6902-6906, 1983), are completely devoid of this joining system. Nonhomologous DNA end-to-end joining, however, attains full activity only at an extremely late stage of egg maturation. Cycloheximide inhibition patterns indicate that nonhomologous joining activity is regulated at the G2 restriction point of the cell cycle. Implications of homologous and nonhomologous recombination activities during egg maturation are discussed.
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