Evidence map›Paper›PMID 17326329›Full record

ReviewVascular health and risk management2006

Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease.

Raed Osman, Philippe L L'Allier, Nader Elgharib, Jean-Claude Tardif

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Vascular health and risk management, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Role of C-Reactive Protein, An Inflammatory Biomarker in The Development of Atherosclerosis and Its Treatment.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raed OsmanDepartment of Medicine, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada.
Philippe L L'Allier
Nader Elgharib
Jean-Claude Tardif

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinicians involved in the care of patients with cardiovascular conditions have recently been confronted with an important body of literature linking inflammation and cardiovascular disease. Indeed, the level of systemic inflammation as measured by circulating levels of C-reactive protein (CRP) has been linked to prognosis in patients with atherosclerotic disease, congestive heart failure, atrial fibrillation, myocarditis, aortic valve disease and heart transplantation. In addition, a number of basic science reports suggest an active role for CRP in the pathophysiology of cardiovascular diseases. This article explores the potential role of CRP in disease initiation, progression, and clinical manifestations and reviews its role in the prediction of future events in clinical practice. Therapeutic interventions to decrease circulating levels of CRP are also reviewed.

Indexed as

Atrial FibrillationCardiovascular DiseasesCoronary DiseaseC-Reactive ProteinDisease ProgressionEndothelium, VascularHeart FailureHeart TransplantationHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLipoproteins, LDLMyocardial RevascularizationMyocarditisPlatelet Aggregation InhibitorsPrognosisThrombosisC-Reactive ProteinHydroxymethylglutaryl-CoA Reductase InhibitorsLipoproteins, LDLPlatelet Aggregation Inhibitors

Identifiers

PMID17326329
PMCPMC1993979

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.