ArticleJournal of acquired immune deficiency syndromes (1999)2007
Willingness to use microbicides is affected by the importance of product characteristics, use parameters, and protective properties.
Article in Journal of acquired immune deficiency syndromes (1999), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- User-identified gel characteristics: a qualitative exploration of perceived product efficacy of topical vaginal microbicides.Archives of sexual behavior · 2014Trial
- Willingness to use microbicides among females who use unregulated drugs in Vancouver, Canada.AIDS care · 2026Article
- Assessing the Acceptability of a Tenofovir-Based Rectal Microbicide Douche among Young Men who Have Sex with Men: Results from ATN-DREAM (ATN 163).AIDS and behavior · 2025Article
- Who prefers what? Correlates of preferences for next-generation HIV prevention products among a national U.S. sample of young men who have sex with men.Journal of the International AIDS Society · 2023Article
- A Brief History and Advancement of Contraceptive Multipurpose Prevention Technology (cMPT) Products.Open access journal of contraception · 2023Review
- Users' Preferred Characteristics of Vaginal Rings for HIV Prevention: A Qualitative Analysis of Two Phase I Trials.AIDS research and human retroviruses · 2022Article
- Development of multipurpose technologies products for pregnancy and STI prevention: update on polyphenylene carboxymethylene MPT gel development†.Biology of reproduction · 2020Article
- Qualitative exploration of intrinsic and extrinsic factors that influence acceptability of semisoft vaginal suppositories.BMC women's health · 2018Article
- Psychometric Properties and Validity of a Multi-dimensional Risk Perception Scale Developed in the Context of a Microbicide Acceptability Study.Archives of sexual behavior · 2016Article
- Designing preclinical perceptibility measures to evaluate topical vaginal gel formulations: relating user sensory perceptions and experiences to formulation properties.AIDS research and human retroviruses · 2014Article
- Designing a multipurpose technology for acceptability and adherence.Antiviral research · 2013Review
- Measuring self-efficacy to use vaginal microbicides: the Microbicide Use Self-Efficacy instrument.Sexual health · 2013Article
- Microbicide clinical trial adherence: insights for introduction.Journal of the International AIDS Society · 2013Review
- Using integrated mixed methods to develop behavioral measures of factors associated with microbicide acceptability.Qualitative health research · 2011Article
- Clinical evaluation of microbicide formulations.Antiviral research · 2010Review
- Increasing the effectiveness of vaginal microbicides: a biophysical framework to rethink behavioral acceptability.PloS one · 2010Article
- Microbicide acceptability among female sex workers in Beijing, China: results from a pilot study.Journal of women's health (2002) · 2009Article
- Effect of acculturation on the acceptability of potential microbicides and sexual risk-taking.Sexually transmitted diseases · 2009Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundAlong with efficacy, a microbicide's acceptability will be integral to its impact on the pandemic. Understanding Product Characteristics that users find most acceptable and determining who will use which type of product are key to optimizing use effectiveness.
objectivesTo evaluate psychometrically the Important Microbicide Characteristics (IMC) instrument and examine its relationship to willingness to use microbicides.
resultsExploratory and confirmatory factor analyses revealed 2 IMC subscales (Cronbach's coefficient alpha: Product Characteristics subscale (alpha = 0.84) and Protective Properties subscale (alpha = 0.89)). Significant differences on Product Characteristics subscale scores were found for history of douching (P = 0.002) and employment status (P = 0.001). Whether a woman used a method to prevent pregnancy or sexually transmitted disease (STD) in the last 3 months (P < 0.001) and whether she used a condom during the last vaginal sex episode (P < 0.001) were significantly related to her rating of the importance of microbicides being contraceptive. Product Characteristics (r = 0.21) and Protective Properties (r = 0.27) subscale scores and whether a microbicide had contraceptive properties (r = 0.24) were all significantly associated (P < 0.001) with willingness to use microbicides.
conclusionsFormulation and use characteristics and product function(s) affect willingness to use microbicides and should continue to be addressed in product development. The IMC instrument serves as a template for future studies of candidate microbicides.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.