Evidence map›Paper›PMID 17323107›Full record

Trial reportOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2007

Impaired geometric properties of tibia in older women with hip fracture history.

T Mikkola, S Sipilä, E Portegijs, M Kallinen, M Alén, I Kiviranta, M Pekkonen, A Heinonen

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Thigh Muscle Composition and Its Relationship to Functional Recovery Post Hip Fracture Over Time and Between Sexes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Asymmetry in CT Scan Measures of Thigh Muscle 2 Months After Hip Fracture: The Baltimore Hip Studies.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015
    Article
  9. Asymmetry in CT Scan Measures of Thigh Muscle 2 Months After Hip Fracture: The Baltimore Hip Studies.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015
    Article
  10. Article
  11. Bone strength measured by peripheral quantitative computed tomography and the risk of nonvertebral fractures: the osteoporotic fractures in men (MrOS) study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2011
    Article
  12. The future is physio ….Physiotherapy Canada. Physiotherapie Canada · 2011
    Article
  13. Women with hip fracture experience greater loss of geometric strength in the contralateral hip during the year following fracture than age-matched controls.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010
    Article
  14. Age and sex differences in estimated tibia strength: influence of measurement site.Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

T MikkolaDepartment of Health Sciences, University of Jyväskylä, P.O. Box 35, Viveca, 40014 Jyväskylä, Finland. tuija.mikkola@sport.jyu.fi
S Sipilä
E Portegijs
M Kallinen
M Alén
I Kiviranta
M Pekkonen
A Heinonen
University of Jyväskylä · FICentral Finland Health Care District · FIAava Medical Centre · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThis study evaluated side-to-side differences in tibial mineral mass and geometry in women with previous hip fracture sustained on average 3.5 years earlier. Both tibial mineral mass and geometry were found to be reduced in the fractured leg.

introductionThe purpose of this study was to evaluate side-to-side differences in tibial mineral mass and geometry after hip fracture and to assess the determinants of such differences.

methodsThirty-eight 60- to 85-year-old women with a previous hip fracture and 22 same-aged control women without fractures participated in the study. Bone characteristics of the distal tibia and tibial shaft of both legs were assessed using pQCT in order to compare the side-to-side differences of tibias between the two groups.

resultsThe subjects with fracture history had significantly (p < OR = 0.05, analysis of covariance) larger side-to-side differences than the controls in tibial shaft BMC (-4.9% vs. -0.5%), cortical area (-5.2% vs. 0.1%) and polar moment of inertia (I(polar)) (-5.6% vs. -0.8%) and in distal tibia BMC (-5.1% vs. -1.4%) and I(polar) (-7.5% vs. -2.4%). In the fracture patients, the side-to-side differences in muscle characteristics explained 23 to 44% of the variances in the side-to-side differences in bone mass and geometry.

conclusionsHip fracture results in reduced bone mass and impaired bone geometry in the tibia of the affected limb in older women. Muscle-induced loading may have a considerable role in the recovery of bone mineral mass and geometry after hip fracture.

Indexed as

AgedAged, 80 and overAgingBone DensityFemaleFemoral Neck FracturesFractures, SpontaneousHip FracturesHumansKnee JointLegMiddle AgedMuscle, SkeletalMuscle StrengthTibiaTomography, X-Ray Computed

Identifiers

PMID17323107
OpenAlexW2111344398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.