ArticlePediatric nephrology (Berlin, Germany)2007
Sterile pyuria in patients with Kawasaki disease originates from both the urethra and the kidney.
Article in Pediatric nephrology (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
- Urinary exosomal microRNAs in Kawasaki disease and their changes after treatment.Pediatric research · 2026Article
- The predictive value of urinary albumin-to-creatinine ratio for coronary artery abnormalities in Kawasaki disease.Frontiers in pediatrics · 2025Article
- Use of Machine Learning to Differentiate Children With Kawasaki Disease From Other Febrile Children in a Pediatric Emergency Department.JAMA network open · 2023Article
- Sterile Pyuria in Kawasaki Disease: A Large Prospective Cohort Study.Frontiers in cardiovascular medicine · 2022Article
- Early features of Kawasaki disease with pyuria in febrile infants younger than 6 months.BMC pediatrics · 2018Article
- Differentiating Kawasaki disease from urinary tract infection in febrile children with pyuria and C-reactive protein elevation.Italian journal of pediatrics · 2018Article
- Clinical features of acute kidney injury in patients with Kawasaki disease.World journal of clinical pediatrics · 2018Review
- Relapse of nephrotic syndrome triggered by Kawasaki disease.CEN case reports · 2018Article
- The emergence of Kawasaki disease in India and China.Global cardiology science & practice · 2017Review
- An atypical case of a 2-year-old boy with acute kidney injury: a race against time. Answers.Pediatric nephrology (Berlin, Germany) · 2017Article
- Urinary Lactate Dehydrogenase Activity and Its Isozyme Patterns in Kawasaki Disease.International journal of pediatrics · 2017Article
- [Renal artery injury caused by Kawasaki disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016Review
- Sterile pyuria: a forgotten entity.Therapeutic advances in urology · 2015Review
- Pyuria in patients with Kawasaki disease.World journal of clinical pediatrics · 2015Review
- Management of Kawasaki disease.Archives of disease in childhood · 2014Review
- Predictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease.Korean journal of pediatrics · 2013Article
- Kidney and urinary tract involvement in kawasaki disease.International journal of pediatrics · 2013Review
- Nephrotic syndrome in Kawasaki disease: a report of three cases.Pediatric nephrology (Berlin, Germany) · 2012Article
- Pyuria associated with acute Kawasaki disease and fever from other causes.The Pediatric infectious disease journal · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To identify the origin of urinary leukocytes in Kawasaki disease (KD) patients with pyuria, we prospectively studied clinical and laboratory findings of 23 KD patients. Patients were divided into three groups: patients without pyuria, patients with pyuria in both voided urine and bladder urine obtained by transurethral catheterization (bladder pyuria) and patients with pyuria only in voided urine (urethral pyuria). Pyuria in voided urine was found in ten of 23 KD patients (43.5%), with subsequent urine cultures proving sterile. Five out of ten patients with pyuria in voided urine also exhibited pyuria in bladder urine, whilst the remaining patients did not have pyuria in bladder urine. Urinary protein levels were higher in patients with bladder pyuria and in patients with urethral pyuria than in patients without pyuria. Urinary beta2-microglobulin concentrations and serum blood urea nitrogen (BUN) and creatinine levels were higher in patients with bladder pyuria than in patients with urethral pyuria or in patients without pyuria, although the serum BUN and creatinine levels of patients with bladder pyuria were within the normal ranges. These results suggest that some patients with KD develop sterile pyuria that originates from the urethra and/or the kidney as a result of mild and subclinical renal injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.