ArticleThe Plant cell2007
Thioredoxin h5 is required for victorin sensitivity mediated by a CC-NBS-LRR gene in Arabidopsis.
Article in The Plant cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 117 citations in OpenAlex.
- Understanding the Role of Durum Wheat ThioredoxinPlants (Basel, Switzerland) · 2026Article
- Review
- Genome-wide linkage mapping of Fusarium crown rot in common wheat (Frontiers in plant science · 2024Article
- The Arabidopsis thioredoxin TRXh5regulates the S-nitrosylation pattern of the TIRK receptor being both proteins essential in the modulation of defences to Tetranychus urticae.Redox biology · 2023Article
- Functional Characterization ofInternational journal of molecular sciences · 2023Article
- Ambivalent response in pathogen defense: A double-edged sword?Plant communications · 2022Review
- Focus on Nitric Oxide Homeostasis: Direct and Indirect Enzymatic Regulation of Protein Denitrosation Reactions in Plants.Antioxidants (Basel, Switzerland) · 2022Review
- Selective redox signaling shapes plant-pathogen interactions.Plant physiology · 2021Review
- Article
- Identification ofFrontiers in genetics · 2020Article
- Identification of candidate genes responsible for the susceptibility of apple (Malus × domestica Borkh.) to Alternaria blotch.BMC plant biology · 2019Article
- Manipulation of Phytohormone Pathways by Effectors of Filamentous Plant Pathogens.Frontiers in plant science · 2019Review
- Transcriptome Analysis and Functional Identification ofThe plant genome · 2018Article
- The major leaf ferredoxin Fd2 regulates plant innate immunity in Arabidopsis.Molecular plant pathology · 2018Article
- The Ralstonia solanacearum type III effector RipAY targets plant redox regulators to suppress immune responses.Molecular plant pathology · 2018Article
- Phytohormone pathways as targets of pathogens to facilitate infection.Plant molecular biology · 2016Review
- The Thioredoxin GbNRX1 Plays a Crucial Role in Homeostasis of Apoplastic Reactive Oxygen Species in Response to Verticillium dahliae Infection in Cotton.Plant physiology · 2016Article
- Contrasting Regulation of NO and ROS in Potato Defense-Associated Metabolism in Response to Pathogens of Different Lifestyles.PloS one · 2016Article
- Genetic Determinism of Sensitivity to Corynespora cassiicola Exudates in Rubber Tree (Hevea brasiliensis).PloS one · 2016Article
- Functional characterization of a Nudix hydrolase AtNUDX8 upon pathogen attack indicates a positive role in plant immune responses.PloS one · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fungus Cochliobolus victoriae causes Victoria blight of oats (Avena sativa) and is pathogenic due to its production of victorin, which induces programmed cell death in sensitive plants. Victorin sensitivity has been identified in Arabidopsis thaliana and is conferred by the dominant gene LOCUS ORCHESTRATING VICTORIN EFFECTS1 (LOV1), which encodes a coiled-coil-nucleotide binding site-leucine-rich repeat protein. We isolated 63 victorin-insensitive mutants, including 59 lov1 mutants and four locus of insensitivity to victorin1 (liv1) mutants. The LIV1 gene encodes thioredoxin h5 (ATTRX5), a member of a large family of disulfide oxidoreductases. To date, very few plant thioredoxins have been assigned specific, nonredundant functions. We found that the victorin response was highly specific to ATTRX5, as the closely related ATTRX3 could only partially compensate for loss of ATTRX5, even when overexpressed. We also created chimeric ATTRX5/ATTRX3 proteins, which identified the central portion of the protein as important for conferring specificity to ATTRX5. Furthermore, we found that ATTRX5, but not ATTRX3, is highly induced in sensitive Arabidopsis following victorin treatment. Finally, we determined that only the first of the two active-site Cys residues in ATTRX5 is required for the response to victorin, suggesting that ATTRX5 function in the victorin pathway involves an atypical mechanism of action.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.