ArticleDrug and alcohol dependence2007
The impact of illicit drug use and harmful drinking on quality of life among injection drug users at high risk for hepatitis C infection.
Article in Drug and alcohol dependence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Cost effectiveness of hepatitis C-related interventions targeting substance users and other high-risk groups: a systematic review.PharmacoEconomics · 2012Pooled it
- Clinical correlates of health-related quality of life among opioid-dependent patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2011Trial
- Effects of a hepatitis C virus educational intervention or a motivational intervention on alcohol use, injection drug use, and sexual risk behaviors among injection drug users.American journal of public health · 2009Trial
- Estimating the health-related quality of life burden attributable to illicit drug use in Australian adults.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Patterns of Health-related Quality of Life in Men Who Inject Drugs: A Survey in Southeast Iran.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Article
- Movement Disorders and Liver Disease.Movement disorders clinical practice · 2021Review
- Concurrent Alcohol and Opioid Use Among Harm Reduction Clients.Addictive behaviors · 2020Article
- The Discrimination Against, Health Status and Wellness of People Who Use Drugs in Italian Services: A Survey.Medicina (Kaunas, Lithuania) · 2019Article
- Overlapping epidemics of alcohol and illicit drug use among HCV-infected persons who inject drugs.Addictive behaviors · 2019Observational
- State-Targeted Funding and Technical Assistance to Increase Access to Medication Treatment for Opioid Use Disorder.Psychiatric services (Washington, D.C.) · 2018Article
- The role of dual diagnosis in health-related quality of life among treatment-seeking patients in Spain.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Article
- Treating Opioid Dependence with Buprenorphine in the Safety Net: Critical Learning from Clinical Data.The journal of behavioral health services & research · 2017Article
- Article
- Effects of family-centered empowerment model based education program on quality of life in methamphetamine users and their families.Iranian Red Crescent medical journal · 2014Article
- Psychometric properties of the World Health Organization Quality Of Life Assessment-Brief in methadone patients: a validation study in northern Taiwan.Harm reduction journal · 2013Article
- Hazardous alcohol consumption among young adult IDU and its association with high risk behaviors.Drug and alcohol dependence · 2013Article
- Current quality of life and its determinants among opiate-dependent individuals five years after starting methadone treatment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2011Article
- Effect of methamphetamine dependence on everyday functional ability.Addictive behaviors · 2010Article
- Factors influencing quality of life of people living with HIV in Estonia: a cross-sectional survey.Journal of the International AIDS Society · 2009Article
- Health-related quality of life in HIV-infected patients: the role of substance use.AIDS patient care and STDs · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHeavy alcohol use, hepatitis C and illicit drug use each have been shown to have negative impacts on health-related quality of life (HRQL). To date, considerations of HRQL have not played a prominent role in the design and measurement of intervention strategies for out-of-treatment at-risk populations.
methodsData were collected from out-of-treatment IDUs recruited through street outreach in North Carolina. Multiple linear regression analyses were used to examine the independent effects of HCV status, harmful drinking (AUDIT), and illicit drug use on HRQL (SF-36).
resultsFifty-one percent of 619 study participants tested HCV-positive; 57% met criteria for harmful or hazardous drinking and 63% reported daily use of hard drugs. HRQL scores for this population were significantly lower than those of the general population. Multiple linear regression analyses demonstrated that harmful levels of alcohol consumption and use of methamphetamine in the past month had the strongest associations with reduced HRQL.
conclusionsGiven the high rates of HCV in most IDU communities, new harm reduction approaches are needed for these populations which focus beyond prevention to the functioning and well being of those already infected. In particular, reducing heavy alcohol use in addition to slowing HCV progression shows promise for improving HRQL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.