Evidence map›Paper›PMID 17319466›Full record

ReviewVascular health and risk management2006

Noninvasive assessment of preclinical atherosclerosis.

Helen A Lane, Jamie C Smith, J Stephen Davies

Registry-linked trialAbstract readReview
In one paragraph

Review in Vascular health and risk management, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01250275 (Effects of Canola Oil on Blood Vessel Function in Peripheral Arterial Disease), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01250275 nacompletednot on this mapstarted 2011, after this paper: background citation

Effects of Canola Oil on Blood Vessel Function in Peripheral Arterial Disease (PAD)

TypeinterventionalSponsorUniversity of ManitobaRan2011 to 2013Enrolled53ConditionsPeripheral Arterial DiseaseArmstraditional canola oil, high oleic canola oil, soybean oil, high linoleic safflower oil, coconut oil
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Lysosome Function in Cardiovascular Diseases.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2021
    Review
  7. Increased arterial stiffness in males with abdominal aortic aneurysm.Clinical physiology and functional imaging · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Cerebral arterial stiffness for predicting functional outcome in acute ischemic stroke.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Observational
  12. Article
  13. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase.Biochimica et biophysica acta. Molecular basis of disease · 2017
    Article
  14. Article
  15. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase.Journal of molecular and cellular cardiology · 2016
    Article
  16. Article
  17. Article
  18. Osteoprotegerin as a marker of atherosclerosis in diabetic patients.International journal of endocrinology · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Helen A LaneDepartment of Endocrinology, University of Wales College of Medicine, Heath Park, Cardiff, Wales, UK. laneha@cf.ac.uk
Jamie C Smith
J Stephen Davies

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initially considered as a semipermeable barrier separating lumen from vessel wall, the endothelium is now recognised as a complex endocrine organ responsible for a variety of physiological processes vital for vascular homeostasis. These include the regulation of vascular tone, luminal diameter, and blood flow; hemostasis and thrombolysis; platelet and leucocyte vessel-wall interactions; the regulation of vascular permeability; and tissue growth and remodelling. The endothelium modulates arterial stiffness, which precedes overt atherosclerosis and is an independent predictor of cardiovascular events. Unsurprisingly, dysfunction of the endothelium may be considered as an early and potentially reversible step in the process of atherogenesis and numerous methods have been developed to assess endothelial status and large artery stiffness. Methodology includes flow-mediated dilatation of the brachial artery, assessment of coronary flow reserve, carotid intima/media thickness, pulse wave analysis, pulse wave velocity, and plethysmography. This review outlines the various modalities, indications, and limitations of available methods to assess arterial dysfunction and vascular risk.

Indexed as

Coronary AngiographyPlethysmographyUltrasonography, InterventionalAtherosclerosisBiomarkersBlood Coagulation FactorsBlood Flow VelocityBrachial ArteryCardiovascular DiseasesCarotid ArteriesCytokinesElasticityEndothelial CellsEndothelium, VascularHumansLipoproteins, LDLBiomarkersBlood Coagulation FactorsCytokinesLipoproteins, LDLoxidized low density lipoprotein

Identifiers

PMID17319466
PMCPMC1993970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.