Evidence map›Paper›PMID 17318426›Full record

ArticleVirus genes2007

Partial 3D gene sequences of Coxsackie viruses reveal interspecies exchanges.

Eugenia Bolanaki, Christine Kottaridi, Panayotis Markoulatos, Zaharoula Kyriakopoulou, Lukas Margaritis, Theodoros Katsorchis

Abstract read
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Article in Virus genes, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eugenia BolanakiDepartment of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimioupolis, Athens, Greece.
Christine Kottaridi
Panayotis Markoulatos
Zaharoula Kyriakopoulou
Lukas Margaritis
Theodoros Katsorchis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 3D region of 46 clinical Coxsackievirus strains, primarily belonging to the human enterovirus B species (HEV-B), were analyzed using nucleotide distance matrices and phylogeny software. The conclusions from previously analyzed genomic regions (VP1-2A-2B-2C) of the aforementioned strains revealed that enteroviruses' inheritance is being guided by gene adaptation among viruses of different serotypes. In this report the comparison of partial VP1 and 3D gene phylogenies presented an obvious incongruence. Moreover, the phylogeny of 3D sequences of the strains revealed an unexpected (and for the first time reported) homology among strains of different species. The observations of our study indicate that conversion events such as multiple mutations or recombination among strains and unknown donors may occur during the evolution of circulating strains, leading, probably, to viruses with altered genome and virulence.

Indexed as

Evolution, MolecularSpecies SpecificityAnimalsCell Line, TumorEnterovirusGene Transfer, HorizontalHumansMolecular Sequence DataPhylogenyRecombination, GeneticSerotyping

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.