Evidence map›Paper›PMID 17318389›Full record

ArticleDigestive diseases and sciences2007

Biochemical markers of bone metabolism in children with Helicobacter pylori infection.

Sebahat Ozdem, Mustafa Akcam, Aygen Yilmaz, Meral Gultekin, Reha Artan

Abstract read
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Article in Digestive diseases and sciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Bone Fragility in Gastrointestinal Disorders.International journal of molecular sciences · 2022
    Review
  2. Review
  3. Article
  4. Article
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  7. Article
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  10. Review
  11. Chronic gastritis and bone mineral density in women.Digestive diseases and sciences · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebahat OzdemCentral Laboratory, Clinical Biochemistry Unit, Akdeniz University, Medical Faculty, 07070 Antalya, Turkey. ozdem@akdeniz.edu.tr
Mustafa Akcam
Aygen Yilmaz
Meral Gultekin
Reha Artan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the biochemical markers of bone metabolism in children with Helicobacter pylori infection. Biochemical markers of bone metabolism and serum levels of vitamin B12, ferritin and estradiol were measured in 41 H. pylori-positive (+) children (23 girls, 18 boys; aged 11.8+/-3 years). Serum levels of intact parathyroid hormone, ss-collagen I carboxy terminal telopeptide, total alkaline phosphatase (ALP), bone-specific ALP, N-terminal cross-links of human procollagen type I, N-mid-osteocalcin, calcium, phosphate, ferritin, and estradiol did not differ significantly between H. pylori(+) and H. pylori negative (-) children. Vitamin B12 levels were significantly decreased in H. pylori(+) compared to H. pylori(-) children. H. pylori infection was not accompanied by significant changes in markers of bone metabolism in children, although vitamin B12 levels were decreased. Further studies are required to clarify whether H. pylori infection causes time-dependent changes in bone turnover markers during the long course of this inflammatory disease.

Indexed as

Helicobacter pyloriAdolescentBiomarkersBone and BonesBone RemodelingChildChild, PreschoolCollagen Type IEstradiolFemaleFerritinsGastritisHelicobacter InfectionsHumansMaleParathyroid HormoneBiomarkersCollagen Type Icollagen type I trimeric cross-linked peptideEstradiolFerritinsParathyroid HormonePeptidesVitamin B 12

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.